Synthetic Biology-Guided Metabolic Engineering

236.5K

views

55

authors

14

articles

Synthetic Biology-Guided Metabolic Engineering

236.5K

views

55

authors

14

articles

Editorial

20 March 2020

Editorial: Synthetic Biology-Guided Metabolic Engineering

Rodrigo Ledesma-Amaro

,

Pablo I. Nikel

and

Francesca Ceroni

4,363 views

3 citations

Editors

3

Rodrigo Ledesma-Amaro

Imperial College London

Pablo Ivan Nikel

Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)

Francesca Ceroni

Imperial College London

Impact

About

Synthetic biology aims at making biology an engineering discipline by turning molecular and cellular behaviours into a more controllable, standardized and predictable set of features. Metabolic engineering seeks to reprogram the metabolic wiring in a cell in order to expand, improve or modify its natural properties for useful purposes such as , for example, maximizing the production of a target compound or degrading a pollutant in an efficient way. In the last few years, a steady increase of synthetic biology-inspired approaches for metabolic engineering has enabled researchers in the field to adopt a truly rational methodology to reprogram the cell behavior.

This Research Topic is intended to collect research articles, method articles, technology reports, reviews, mini-reviews, perspective or opinion articles on how the recent technical advances in synthetic biology (such as DNA assembly, genome synthesis, sequencing and NGS, genetic engineering, control theory, metabolic modeling, genome editing, orthogonality and fine control of gene expression), can be used to manipulate the metabolism of target cells in a more efficient, faster and reliable manner.

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Editors

Rodrigo Ledesma-Amaro

Imperial College London

Pablo Ivan Nikel

Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)

Francesca Ceroni

Imperial College London

Impact

236,522 Total views

199,359 Article views

33,218 Article downloads

3,945 Topic views

Published In

Frontiers in Bioengineering and Biotechnology

Synthetic Biology

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