About this Research Topic
The development and maturation of ovarian follicles are critical processes in female fertility, tightly regulated by intricate endocrine signaling pathways. Dysregulation in these processes can lead to compromised ovarian function, infertility, and other reproductive disorders. Understanding the cellular and molecular mechanisms that govern follicular development and oocyte maturation is essential for advancing reproductive health and developing novel therapeutic interventions.
This research topic aims to explore the endocrine regulation of ovarian function, focusing on how molecular mechanisms within granulosa cells and other ovarian compartments influence follicular development, oocyte maturation, and hormonal interactions. It encourages submissions investigating the complex cross-talk between signaling pathways, microRNAs, and regulatory proteins that maintain the balance of these processes under physiological conditions.
In this Research Topic, we invite contributors to submit papers on the following topics, including but not limited to:
• Investigation of molecular pathways regulating granulosa cell function in follicle development.
• Role of endocrine signals in oocyte maturation and meiotic progression.
• MicroRNAs as key regulators of granulosa cell function and ovarian follicle dynamics.
• Cross-talk between endocrine signaling pathways during follicular growth.
• Mechanisms controlling primordial follicle recruitment and growth.
• Impact of endocrine disruptions on ovarian function and fertility outcomes.
This research topic aims to explore the endocrine regulation of ovarian function, focusing on how molecular mechanisms within granulosa cells and other ovarian compartments influence follicular development, oocyte maturation, and hormonal interactions. It encourages submissions investigating the complex cross-talk between signaling pathways, microRNAs, and regulatory proteins that maintain the balance of these processes under physiological conditions.
In this Research Topic, we invite contributors to submit papers on the following topics, including but not limited to:
• Investigation of molecular pathways regulating granulosa cell function in follicle development.
• Role of endocrine signals in oocyte maturation and meiotic progression.
• MicroRNAs as key regulators of granulosa cell function and ovarian follicle dynamics.
• Cross-talk between endocrine signaling pathways during follicular growth.
• Mechanisms controlling primordial follicle recruitment and growth.
• Impact of endocrine disruptions on ovarian function and fertility outcomes.
Keywords: Ovarian Follicle Development, Oocyte Maturation, Endocrine Regulation, Granulosa Cells, Molecular Mechanisms, Fertility, Signaling Pathways, MicroRNAs, Primordial Follicle Recruitment, Endocrine Disruptions, Extracellular Vesicles
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
