The treatment of spinal cord injuries has consistently been a focal point of international medical studies, attracting sweeping attention across global research communities. Recent breakthroughs reveal that several programmed death pathways, like necroptosis, pyroptosis, ferroptosis, and parthanatos, are critically implicated in the pathology of spinal cord injuries. Although these discoveries mark significant progress, the development of therapies that effectively target these pathways remains largely unmet, indicating a clear gap in current treatment modalities that demand innovative solutions and further refinement.This research topic is driven by the objective of consolidating international research efforts to advance and devise novel therapeutic strategies that specifically address these innovative programmed death pathways. By harnessing global scientific knowledge and technology, the initiative aspires to catalyze major scientific and technological breakthroughs in the realm of spinal cord injury treatments.1. Research on the mechanisms of novel programmed death pathways in spinal cord injury2. Development of small molecule drugs and biological therapies targeting Necroptosis, pyroptosis, ferroptosis, and parthanatos pathways3. Preclinical and clinical studies of novel programmed death pathway inhibitors, and their potential applications in the treatment of spinal cord injury4. The interaction between novel programmed death pathways and spinal cord injury, and their therapeutic significance5. Experimental models and clinical translation of new therapeutic strategies based on novel programmed death pathways6. The role of traditional Chinese medicine in regulating programmed death pathways and its application prospects in modern treatment
The treatment of spinal cord injuries has consistently been a focal point of international medical studies, attracting sweeping attention across global research communities. Recent breakthroughs reveal that several programmed death pathways, like necroptosis, pyroptosis, ferroptosis, and parthanatos, are critically implicated in the pathology of spinal cord injuries. Although these discoveries mark significant progress, the development of therapies that effectively target these pathways remains largely unmet, indicating a clear gap in current treatment modalities that demand innovative solutions and further refinement.This research topic is driven by the objective of consolidating international research efforts to advance and devise novel therapeutic strategies that specifically address these innovative programmed death pathways. By harnessing global scientific knowledge and technology, the initiative aspires to catalyze major scientific and technological breakthroughs in the realm of spinal cord injury treatments.1. Research on the mechanisms of novel programmed death pathways in spinal cord injury2. Development of small molecule drugs and biological therapies targeting Necroptosis, pyroptosis, ferroptosis, and parthanatos pathways3. Preclinical and clinical studies of novel programmed death pathway inhibitors, and their potential applications in the treatment of spinal cord injury4. The interaction between novel programmed death pathways and spinal cord injury, and their therapeutic significance5. Experimental models and clinical translation of new therapeutic strategies based on novel programmed death pathways6. The role of traditional Chinese medicine in regulating programmed death pathways and its application prospects in modern treatment