Neuroinflammation: Mechanisms and Therapeutic Interventions

111.5K

views

62

authors

26

articles

Neuroinflammation: Mechanisms and Therapeutic Interventions

111.5K

views

62

authors

26

articles

Editorial

24 March 2026

Editorial: Neuroinflammation: mechanisms and therapeutic interventions

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Neuroinflammation has emerged as a pivotal area of study over recent decades, propelled by its critical involvement in both healthy brain functionality and various diseases. The interchange between immune molecules and cells within the brain underscores many neurophysiological and pathophysiological processes. There has been a considerable push to elucidate the cellular and molecular pathways that catalyze neuroinflammation because understanding these pathways is of paramount importance for conceptualizing therapeutic interventions that can alleviate the adverse long-term consequences on brain and systemic health, while elucidating fundamental neurodevelopmental mechanisms.

This research topic aims to explore the unresolved intricacies of neuroinflammation, focusing on how it governs neuroimmune responses both in the presence of disease and during normal physiological conditions. The goal is to gather research that outlines possible initiators of neuroinflammatory responses and the signaling pathways involved, aiming at revealing novel molecular targets and innovative therapeutic avenues that could potentially curb or enhance the prognosis of inflammatory neurodegenerative and neurological disorders.

Scope-wise, to amass a richer understanding of this complex subject, submissions are encouraged that fit within, but are not limited to, the following subthemes:
o Genetic and environmental triggers of neuroinflammation
o Molecular and cellular mechanisms underpinning neuroinflammatory processes
o Innovative therapeutic targets and strategic interventions for managing neuroinflammation
o The role of lifestyle factors in influencing neuroinflammation and cognitive health

Neuroinflammation has emerged as a pivotal area of study over recent decades, propelled by its critical involvement in both healthy brain functionality and various diseases. The interchange between immune molecules and cells within the brain underscores many neurophysiological and pathophysiological processes. There has been a considerable push to elucidate the cellular and molecular pathways that catalyze neuroinflammation because understanding these pathways is of paramount importance for conceptualizing therapeutic interventions that can alleviate the adverse long-term consequences on brain and systemic health, while elucidating fundamental neurodevelopmental mechanisms.

This research topic aims to explore the unresolved intricacies of neuroinflammation, focusing on how it governs neuroimmune responses both in the presence of disease and during normal physiological conditions. The goal is to gather research that outlines possible initiators of neuroinflammatory responses and the signaling pathways involved, aiming at revealing novel molecular targets and innovative therapeutic avenues that could potentially curb or enhance the prognosis of inflammatory neurodegenerative and neurological disorders.

Scope-wise, to amass a richer understanding of this complex subject, submissions are encouraged that fit within, but are not limited to, the following subthemes:
o Genetic and environmental triggers of neuroinflammation
o Molecular and cellular mechanisms underpinning neuroinflammatory processes
o Innovative therapeutic targets and strategic interventions for managing neuroinflammation
o The role of lifestyle factors in influencing neuroinflammation and cognitive health

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Mayra A. Machuca

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Frontiers in Immunology

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Frontiers in Pharmacology

Ethnopharmacology

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