About this Research Topic
Cell adhesion molecules (CAMs) are crucial for maintaining cellular integrity and facilitating communication between cells and their environments. In cancer, these molecules do more than mediate physical interactions; they actively participate in signaling pathways that reprogram cellular metabolism. This reprogramming supports rapid cancer cell growth and adaptation to varying microenvironmental conditions, promoting tumor progression and metastasis. Understanding how CAMs influence cancer metabolism can reveal new therapeutic targets and strategies to combat cancer more effectively. This research topic focuses on dissecting the roles of CAMs in altering metabolic pathways in cancer cells, emphasizing their potential as pivotal regulators in both tumor survival and the response to treatments.
Contributions should investigate how CAMs modulate metabolic pathways to promote cancer cell survival, growth, and metastasis. We seek studies that elucidate the molecular mechanisms by which CAMs integrate into cancer metabolism, including how they regulate glucose uptake, energy production, and anabolic processes necessary for tumor growth. This topic encourages submissions that utilize advanced methodologies such as live-cell imaging, metabolic profiling, and molecular biology techniques to provide comprehensive insights into CAM functions. Additionally, we are interested in research that examines the interactions between CAMs and the tumor microenvironment, assessing how these relationships affect metabolic strategies of cancer cells and identifying potential points of therapeutic intervention. By understanding these complex interactions, this research topic aims to advance our knowledge of cancer biology and foster the development of novel cancer treatments.
Original research articles, methods, reviews, and mini-reviews are welcome. Specific areas of interest for the topic include but are not limited to the following:
1. Empirical research detailing CAMs' role in key metabolic pathways in cancer.
2. Theoretical analyses of CAMs’ influence on cancer cell metabolism.
3. Studies on the tumor microenvironment’s impact on CAM-mediated metabolic changes.
4. Use of cutting-edge imaging and biochemical methods to explore CAM functions.
5. Animal model research clarifying CAMs' effects on tumor biology.
6. Development of therapeutic strategies targeting CAM-related metabolic pathways.
7. Mechanobiological studies on CAM-mediated metabolic reprogramming in cancer, examining how mechanical forces influence metabolic pathways and tumor progression.
Contributions should investigate how CAMs modulate metabolic pathways to promote cancer cell survival, growth, and metastasis. We seek studies that elucidate the molecular mechanisms by which CAMs integrate into cancer metabolism, including how they regulate glucose uptake, energy production, and anabolic processes necessary for tumor growth. This topic encourages submissions that utilize advanced methodologies such as live-cell imaging, metabolic profiling, and molecular biology techniques to provide comprehensive insights into CAM functions. Additionally, we are interested in research that examines the interactions between CAMs and the tumor microenvironment, assessing how these relationships affect metabolic strategies of cancer cells and identifying potential points of therapeutic intervention. By understanding these complex interactions, this research topic aims to advance our knowledge of cancer biology and foster the development of novel cancer treatments.
Original research articles, methods, reviews, and mini-reviews are welcome. Specific areas of interest for the topic include but are not limited to the following:
1. Empirical research detailing CAMs' role in key metabolic pathways in cancer.
2. Theoretical analyses of CAMs’ influence on cancer cell metabolism.
3. Studies on the tumor microenvironment’s impact on CAM-mediated metabolic changes.
4. Use of cutting-edge imaging and biochemical methods to explore CAM functions.
5. Animal model research clarifying CAMs' effects on tumor biology.
6. Development of therapeutic strategies targeting CAM-related metabolic pathways.
7. Mechanobiological studies on CAM-mediated metabolic reprogramming in cancer, examining how mechanical forces influence metabolic pathways and tumor progression.
Keywords: Cell Adhesion Molecules, Cancer Metabolism, Tumor Progression, Metabolic Reprogramming, Therapeutic Targets
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
