About this Research Topic
The development of genomics provides unprecedented opportunities for studying the mechanisms of drug action. Through in-depth analysis of genomic data, scientists can more accurately identify drug targets and further understand the mechanisms of drug action. This not only helps to explain the efficacy of drugs, but also reveals potential drug side effects, providing key guidance information for new drug development.
Network pharmacology is an emerging interdisciplinary research method that combines biological networks, chemicals, and disease states to discover new drug mechanisms and drug combinations. By constructing and analyzing drug target disease networks, network pharmacology can predict the potential mechanisms of action of drugs, discover new drug combinations, and understand the process of drug action in vivo. This helps to reduce the cost and time of drug discovery and improve the efficiency of drug development.
New drug discovery is a challenging field that requires facing numerous issues such as drug efficacy, safety, and side effects. However, the development of gene and network pharmacology has provided new opportunities for the discovery of new drugs. By conducting in-depth research on genomics and drug action mechanisms, as well as applying network pharmacology methods, scientists can more efficiently discover and develop new drugs to address current challenges.
In recent years, an increasing number of successful cases have shown the important role of gene and network pharmacology in the discovery of new drugs. For example, by analyzing genomic data, scientists have discovered a new drug target and developed a new anti-cancer drug based on it. This drug has shown significant efficacy in clinical trials, providing a new option for cancer treatment. In addition, the methods of network pharmacology have also been widely applied in the discovery of new drugs. By constructing a drug target disease network, scientists have discovered new drug combinations and mechanisms of action, providing important guidance for new drug development.
These successful cases not only demonstrate the important value of gene and network pharmacology in new drug discovery, but also provide valuable experience and inspiration for future drug development. With the continuous development of technology, we have reason to believe that gene and network pharmacology will continue to lead revolutionary changes in the discovery of new drugs.
The theme of this special issue will revolve around the research progress of gene and network pharmacology in new drug discovery. We will invite top scholars and experts from around the world to conduct in-depth discussions on topics such as the research progress of genomics and drug action mechanisms, the theory and application of network pharmacology, and the challenges and opportunities of new drug discovery. The editors welcome original research and review articles that focus on related field, but are not limited to, the following themes:
Using proteomics and metabonomics to explain molecular biology related research.
Advances in molecular biology multi-omic integration.
Bioinformatics and experimental verification for molecular biology related research.
Network pharmacology of new drugs combine with molecular biology in treatment of disease.
Disease-related RNA detection, disease gene discovery, regulatory pathway analysis.
Molecular biology treatment evidence-based medicine.
Keywords: network pharmacology, gene, new drug discovery, molecular biology, genome sequencing
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