Systemic Lupus Erythematosus and Antiphospholipid Syndrome

181.7K

views

60

authors

16

articles

Systemic Lupus Erythematosus and Antiphospholipid Syndrome

181.7K

views

60

authors

16

articles

Editorial

25 February 2019

Editorial: Systemic Lupus Erythematosus and Antiphospholipid Syndrome

Pier Luigi Meroni

and

George C. Tsokos

23,950 views

22 citations

Editors

2

Pier Luigi Meroni

Italian Auxological Institute (IRCCS)

George C Tsokos

Harvard Medical School

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About

Systemic Lupus Erythematosus (SLE) is the prototypical autoimmune disease, characterized by an extreme variety of anti-nuclear antibodies and by different clinical presentations. Antiphospholipid Syndrome (APS) is characterized by the presence of arterial or venous thrombosis and anti-phospholipid antibodies. SLE and APS frequently occur within the same patient. Both APS and SLE have unknown etiologies and their pathogenetic mechanism(s) remain poorly understood.

The aim of this Research Topic is to link bench to bed-side research on SLE and APS, to help us unravel the cellular and molecular basis of these diseases, with the ultimate goal of defining new diagnostic and therapeutic tools for SLE and APS. This Research Topic will cover novel findings and reviews that cover topics including, but not limited to:

1. SLE or APS and pregnancy;
2. SLE/APS-associated atherosclerosis and/or thrombosis;
3. Neuropsychiatric involvement in SLE and APS disease;
4. Lymphomas associated with SLE and APS;
5. Novel biomarkers for SLE and APS;
6. Identification of new immune modulators of SLE and APS;
7. The role of immune cells in SLE and APS;
8. The role of the microbiome in SLE and APS and
9. Nanomedicines for SLE and APS treatment.

We welcome the submission of the following article types to this Research Topic: Original Research, Review, Methods, Protocols, Technology Reports, Mini-Review and Clinical Trial.

Systemic Lupus Erythematosus (SLE) is the prototypical autoimmune disease, characterized by an extreme variety of anti-nuclear antibodies and by different clinical presentations. Antiphospholipid Syndrome (APS) is characterized by the presence of arterial or venous thrombosis and anti-phospholipid antibodies. SLE and APS frequently occur within the same patient. Both APS and SLE have unknown etiologies and their pathogenetic mechanism(s) remain poorly understood.

The aim of this Research Topic is to link bench to bed-side research on SLE and APS, to help us unravel the cellular and molecular basis of these diseases, with the ultimate goal of defining new diagnostic and therapeutic tools for SLE and APS. This Research Topic will cover novel findings and reviews that cover topics including, but not limited to:

1. SLE or APS and pregnancy;
2. SLE/APS-associated atherosclerosis and/or thrombosis;
3. Neuropsychiatric involvement in SLE and APS disease;
4. Lymphomas associated with SLE and APS;
5. Novel biomarkers for SLE and APS;
6. Identification of new immune modulators of SLE and APS;
7. The role of immune cells in SLE and APS;
8. The role of the microbiome in SLE and APS and
9. Nanomedicines for SLE and APS treatment.

We welcome the submission of the following article types to this Research Topic: Original Research, Review, Methods, Protocols, Technology Reports, Mini-Review and Clinical Trial.

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Editors

Pier Luigi Meroni

Italian Auxological Institute (IRCCS)

George C Tsokos

Harvard Medical School

Impact

181,665 Total views

115,439 Article views

49,811 Article downloads

16,415 Topic views

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Frontiers in Immunology

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