Systemic Lupus Erythematosus and Antiphospholipid Syndrome

184K

views

60

authors

16

articles

Editorial

25 February 2019

Editorial: Systemic Lupus Erythematosus and Antiphospholipid Syndrome

Pier Luigi Meroni

and

George C. Tsokos

16,923 views

22 citations

Editors

2

Pier Luigi Meroni

Italian Auxological Institute (IRCCS)

George C Tsokos

Harvard Medical School

Impact

About

Systemic Lupus Erythematosus (SLE) is the prototypical autoimmune disease, characterized by an extreme variety of anti-nuclear antibodies and by different clinical presentations. Antiphospholipid Syndrome (APS) is characterized by the presence of arterial or venous thrombosis and anti-phospholipid antibodies. SLE and APS frequently occur within the same patient. Both APS and SLE have unknown etiologies and their pathogenetic mechanism(s) remain poorly understood.

The aim of this Research Topic is to link bench to bed-side research on SLE and APS, to help us unravel the cellular and molecular basis of these diseases, with the ultimate goal of defining new diagnostic and therapeutic tools for SLE and APS. This Research Topic will cover novel findings and reviews that cover topics including, but not limited to:

1. SLE or APS and pregnancy;
2. SLE/APS-associated atherosclerosis and/or thrombosis;
3. Neuropsychiatric involvement in SLE and APS disease;
4. Lymphomas associated with SLE and APS;
5. Novel biomarkers for SLE and APS;
6. Identification of new immune modulators of SLE and APS;
7. The role of immune cells in SLE and APS;
8. The role of the microbiome in SLE and APS and
9. Nanomedicines for SLE and APS treatment.

We welcome the submission of the following article types to this Research Topic: Original Research, Review, Methods, Protocols, Technology Reports, Mini-Review and Clinical Trial.

Systemic Lupus Erythematosus (SLE) is the prototypical autoimmune disease, characterized by an extreme variety of anti-nuclear antibodies and by different clinical presentations. Antiphospholipid Syndrome (APS) is characterized by the presence of arterial or venous thrombosis and anti-phospholipid antibodies. SLE and APS frequently occur within the same patient. Both APS and SLE have unknown etiologies and their pathogenetic mechanism(s) remain poorly understood.

The aim of this Research Topic is to link bench to bed-side research on SLE and APS, to help us unravel the cellular and molecular basis of these diseases, with the ultimate goal of defining new diagnostic and therapeutic tools for SLE and APS. This Research Topic will cover novel findings and reviews that cover topics including, but not limited to:

1. SLE or APS and pregnancy;
2. SLE/APS-associated atherosclerosis and/or thrombosis;
3. Neuropsychiatric involvement in SLE and APS disease;
4. Lymphomas associated with SLE and APS;
5. Novel biomarkers for SLE and APS;
6. Identification of new immune modulators of SLE and APS;
7. The role of immune cells in SLE and APS;
8. The role of the microbiome in SLE and APS and
9. Nanomedicines for SLE and APS treatment.

We welcome the submission of the following article types to this Research Topic: Original Research, Review, Methods, Protocols, Technology Reports, Mini-Review and Clinical Trial.

Download ebook

Share

Editors

Pier Luigi Meroni

Italian Auxological Institute (IRCCS)

George C Tsokos

Harvard Medical School

Impact

183,970 Total views

116,848 Article views

50,472 Article downloads

16,650 Topic views

Published In

Journal Thumbnail

Frontiers in Immunology

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic