Advances in Intra-Abdominal Infection

Intra-abdominal infections represent a significant challenge in medical management and patient care. Recent years have witnessed notable advancements across several key domains of this field. Improved diagnostic techniques, including advanced imaging and molecular diagnostics, have considerably enhanced the accuracy and speed of pathogen identification. The emergence of next-generation sequencing technologies has been pivotal in refining pathogen detection, which in turn facilitates more targeted therapeutic interventions. Additionally, developments in surgical and interventional techniques have improved source control of infections, crucial for preventing the spread and worsening of the condition. Meanwhile, in the management of multi-organ dysfunction and organ function support, advanced strategies and technologies have emerged, improving the prognosis of patients with severe intra-abdominal infections.

This Research Topic aims to spotlight the latest innovations and insights in the diagnosis, treatment, and management of intra-abdominal infections. It seeks to explore a broad spectrum of cutting-edge practices, from new diagnostic tools that improve early detection and identification of pathogens to novel therapeutic approaches including the use of innovative antibiotics and immunotherapies. We highlight the importance of optimal infection source control and effective organ function support. The goal is to provide a comprehensive overview that enhances understanding and guides the development of more effective strategies in combating these infections.
To gather further insights and foster a comprehensive discussion, this Research Topic welcomes contributions that explore a wide array of pertinent themes, including:
o New diagnostic tools and techniques for improving early detection and the accurate identification of pathogens
o Management strategies for antibiotic resistance
o Advances in infection source control
o Progress in multi-organ functional support for critically ill patients with intra-abdominal infections
o Case studies that detail complex infection scenarios, research on novel therapeutics, and reviews of best clinical practices

Keywords: Intra-Abdominal Infection, Liver Abscess, Post-Operative Abdominal Infection, Abdominal Compartment Syndrome, Multiple Organ Dysfunction Syndrome

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.