About this Research Topic
Calcium signaling is a critical area of research within cardiovascular physiology and pathology. The calcium ion (Ca2+) is essential for numerous physiological functions, including muscle contraction, bone formation, enzyme activity, and blood coagulation. It is tightly regulated by hormones to maintain calcium balance within the body. In the cardiovascular system, calcium signaling pathways are crucial for regulating gene expression and cardiomyocyte growth, both in normal development and in disease states. Altered calcium homeostasis is a common feature in cardiovascular diseases, highlighting the importance of understanding calcium signaling modifications as potential therapeutic targets. Despite significant advances, the complex interplay between hormones, calcium homeostasis, and cardiovascular health remains incompletely understood. This underscores the need for further investigation into the mechanisms by which calcium signaling contributes to cardiovascular disease pathogenesis and progression.
This Research Topic aims to explore the intricate relationship between hormones, calcium homeostasis/signaling, and cardiovascular diseases. The primary objective is to identify and understand the mechanisms by which calcium signaling pathways influence cardiovascular health and disease. By examining these pathways, the research seeks to uncover potential therapeutic strategies that could improve calcium regulation and alleviate cardiovascular disease symptoms. Key questions include how hormonal disturbances affect calcium homeostasis and the role of calcium signaling in disease progression.
To gather further insights into the complex interactions between calcium signaling and cardiovascular diseases, we welcome articles addressing, but not limited to, the following themes:
- The mechanism of calcium homeostasis disturbances by hormones in cardiovascular diseases and interventions to stabilize calcium homeostasis.
- The potential role of calcium signaling pathways in cardiovascular diseases.
- The effects of persistent genomic and/or mitochondrial DNA damage on cardiovascular diseases.
- The possible mechanisms via calcium signaling pathways contributing to cardiovascular disease progression.
- Underlying mechanisms of inducing calcium-binding proteins in the endoplasmic reticulum or mitochondria during the occurrence and development of cardiovascular diseases.
This Research Topic aims to explore the intricate relationship between hormones, calcium homeostasis/signaling, and cardiovascular diseases. The primary objective is to identify and understand the mechanisms by which calcium signaling pathways influence cardiovascular health and disease. By examining these pathways, the research seeks to uncover potential therapeutic strategies that could improve calcium regulation and alleviate cardiovascular disease symptoms. Key questions include how hormonal disturbances affect calcium homeostasis and the role of calcium signaling in disease progression.
To gather further insights into the complex interactions between calcium signaling and cardiovascular diseases, we welcome articles addressing, but not limited to, the following themes:
- The mechanism of calcium homeostasis disturbances by hormones in cardiovascular diseases and interventions to stabilize calcium homeostasis.
- The potential role of calcium signaling pathways in cardiovascular diseases.
- The effects of persistent genomic and/or mitochondrial DNA damage on cardiovascular diseases.
- The possible mechanisms via calcium signaling pathways contributing to cardiovascular disease progression.
- Underlying mechanisms of inducing calcium-binding proteins in the endoplasmic reticulum or mitochondria during the occurrence and development of cardiovascular diseases.
Keywords: calcium-binding proteins, mitochondria, heart failure, cardiovascular disease, ryanodine receptor, immune response, inflammation, neutrophil
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
