About this Research Topic
Enamel, dentin, and pulp tissue are central to dental research due to their critical roles in tooth mineralization. Despite extensive research, the mechanisms behind their formation and interaction remain unclear.
Enamel, once formed by ameloblasts, doesn't regenerate, making its preservation imperative. Advances in research on rodent incisors, which regrow continually, have yielded valuable insights. Research on extracted teeth has resulted in significant developments in material science, leading to enamel preservation, caries prevention, repair strategies, and less-damaging bleaching treatments.
Dentin, produced by odontoblasts, can form supplementary dentin in response to external stimuli. The emergence of hydraulic calcium silicate cement and insights into pulp tissue have revolutionized dentin-pulp complex treatments. One such treatment, "vital pulp therapy (VPT)," has proven effective in endodontics, significantly extending the scientific focus.
Although various genes reportedly affect enamel formation, ameloblasts' precise mechanisms remain unclear. Similarly, the responses of odontoblasts and pulp tissues to VPT are partially understood but not fully elucidated.
This Research Topic seeks to pool knowledge on various mineralized tissues involved in formation and wound healing, to enhance our grasp on enamel, dentin, and pulp healing. We welcome original research, reviews, and case reports.
The objective is to reinforce our basic scientific knowledge about enamel and the dentin-pulp complex and establish interconnections among these mineralized tissues. By building on clinical knowledge, we anticipate facilitating the early clinical application of these insights.
Enamel, once formed by ameloblasts, doesn't regenerate, making its preservation imperative. Advances in research on rodent incisors, which regrow continually, have yielded valuable insights. Research on extracted teeth has resulted in significant developments in material science, leading to enamel preservation, caries prevention, repair strategies, and less-damaging bleaching treatments.
Dentin, produced by odontoblasts, can form supplementary dentin in response to external stimuli. The emergence of hydraulic calcium silicate cement and insights into pulp tissue have revolutionized dentin-pulp complex treatments. One such treatment, "vital pulp therapy (VPT)," has proven effective in endodontics, significantly extending the scientific focus.
Although various genes reportedly affect enamel formation, ameloblasts' precise mechanisms remain unclear. Similarly, the responses of odontoblasts and pulp tissues to VPT are partially understood but not fully elucidated.
This Research Topic seeks to pool knowledge on various mineralized tissues involved in formation and wound healing, to enhance our grasp on enamel, dentin, and pulp healing. We welcome original research, reviews, and case reports.
The objective is to reinforce our basic scientific knowledge about enamel and the dentin-pulp complex and establish interconnections among these mineralized tissues. By building on clinical knowledge, we anticipate facilitating the early clinical application of these insights.
Keywords: tooth development, mineralized tissue, regenerative therapies, dental materials, genetics
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