With the prevalence of Alzheimer's disease on the rise among aging populations, it becomes crucial to acquire a comprehensive understanding of the underlying biomechanisms to enhance preventive measures for patients. Recent advances in the elucidation of basic biomechanisms such as the major role of the influential genetic factor TREM2 in the immunological basis of Alzheimer’s disease and the establishment of mechanobiology with relevance to Alzheimer’s diseases, hold promising translational value and potential for clinical applications.
This research topic aims to elucidate the most recent progress in the field of basic and clinical research. Specifically, we will focus on areas such as the pathogenesis of Alzheimer's disease, neurodegenerative processes and early changes, perception and cognition deficits, immune regulation, as well as new therapeutic targets and innovative strategies. The topic editorial team is dedicated to advancing the field of Alzheimer's disease and creating a platform which future progress can be built upon.
This research topic welcomes various article types, including original research, brief research report, systematic review, and mini review. The research topic includes the following areas but not be limited to:
1. New insights into the biomechanism of Alzheimer's disease, including the perspective of recently identified biomacromolecules of interest, such as TREM2 and TNFR2, and mechanobiology-related theories.
2. Novel approaches in the prevention and early diagnosis of Alzheimer's disease based on the new insights into biomechanisms of Alzheimer's disease.
3. Innovative therapeutic targets and strategies toward Alzheimer's disease are made possible by the recent advances in our understanding of the biomechanism of Alzheimer's disease.
With the prevalence of Alzheimer's disease on the rise among aging populations, it becomes crucial to acquire a comprehensive understanding of the underlying biomechanisms to enhance preventive measures for patients. Recent advances in the elucidation of basic biomechanisms such as the major role of the influential genetic factor TREM2 in the immunological basis of Alzheimer’s disease and the establishment of mechanobiology with relevance to Alzheimer’s diseases, hold promising translational value and potential for clinical applications.
This research topic aims to elucidate the most recent progress in the field of basic and clinical research. Specifically, we will focus on areas such as the pathogenesis of Alzheimer's disease, neurodegenerative processes and early changes, perception and cognition deficits, immune regulation, as well as new therapeutic targets and innovative strategies. The topic editorial team is dedicated to advancing the field of Alzheimer's disease and creating a platform which future progress can be built upon.
This research topic welcomes various article types, including original research, brief research report, systematic review, and mini review. The research topic includes the following areas but not be limited to:
1. New insights into the biomechanism of Alzheimer's disease, including the perspective of recently identified biomacromolecules of interest, such as TREM2 and TNFR2, and mechanobiology-related theories.
2. Novel approaches in the prevention and early diagnosis of Alzheimer's disease based on the new insights into biomechanisms of Alzheimer's disease.
3. Innovative therapeutic targets and strategies toward Alzheimer's disease are made possible by the recent advances in our understanding of the biomechanism of Alzheimer's disease.
