RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

130.8K

views

69

authors

12

articles

RNA Diseases in Humans – From Fundamental Research to Therapeutic Applications

130.8K

views

69

authors

12

articles

Editorial

16 July 2019

Editorial: RNA Diseases in Humans—From Fundamental Research to Therapeutic Applications

Naoyuki Kataoka

,

Akila Mayeda

and

Kinji Ohno

4,101 views

3 citations

Editors

3

Naoyuki Kataoka

The University of Tokyo

Nagoya University

Fujita Health University

Impact

About

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications.

In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.

This Research Topic aims at gathering manuscripts addressing diseases caused by defects in RNA metabolism. We particularly welcome studies:
- linking the basic science – i.e. elucidating the molecular mechanisms of RNA regulation – and the implications and applications for therapeutic approaches
- focusing on the potential role of non-coding RNAs in diagnosis and therapy of RNA diseases

We welcome the following article types: Original Research, Reviews, Mini-Reviews, Perspectives, Opinions, and Methods.

This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications.

In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.

This Research Topic aims at gathering manuscripts addressing diseases caused by defects in RNA metabolism. We particularly welcome studies:
- linking the basic science – i.e. elucidating the molecular mechanisms of RNA regulation – and the implications and applications for therapeutic approaches
- focusing on the potential role of non-coding RNAs in diagnosis and therapy of RNA diseases

We welcome the following article types: Original Research, Reviews, Mini-Reviews, Perspectives, Opinions, and Methods.

Download ebook

Share

Editors

Naoyuki Kataoka

The University of Tokyo

Nagoya University

Fujita Health University

Impact

130,766 Total views

93,834 Article views

27,844 Article downloads

9,088 Topic views

Published In

Journal Thumbnail

Frontiers in Molecular Biosciences

Journal Thumbnail

Frontiers in Genetics

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic