About this Research Topic
This Research Topic aims to explore the intricate manifestations, pathogenesis, disease genes, and treatments associated with vascular malformations and related syndromes. This topic will delve into advancements in these areas, address unresolved issues, comprehensively analyze the existing literature, and strive to establish consensus among clinicians and researchers for reference.
We welcome submissions about complex vascular malformations, including venous malformations, arteriovenous malformations, capillary malformations, lymphatic malformations, mixed vascular malformations, and related syndromes such as Klippel-Trenaunay syndrome, Parkes Weber syndrome, Sturge-Weber syndrome, Maffucci syndrome, CLAPO syndrome, Cloves syndrome, and the more complex PIK3CA-related overgrowth syndrome. These topics will be given higher priority:
- In-depth studies of common vascular malformations, encompassing rare clinical phenotypes, novel findings in pathogenesis, and innovative therapies.
- Clinical and basic research on rare vascular malformations and related syndromes, including investigations into clinical phenotypes, pathogenesis, and disease genes.
- Novel treatments for complex vascular malformation-related syndromes, such as targeted therapies targeting genetic mutations and abnormal signaling pathways, or comprehensive treatments based on new materials and drugs.
- Comparative studies of complex vascular malformations and related syndromes across different countries and ethnicities, including new discoveries in clinical phenotypes, disease genes, and variations in treatment response.
Keywords: Vascular Malformation, Manifestation, Pathogenesis, Disease Gene, Treatment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.