Subjective tinnitus is commonly defined as the perception of sound in the absence of an external source. It is an extremely common condition, with prevalence estimates between 10 - 30% worldwide. Despite an increased surge in tinnitus research in recent years, a clear understanding of the neural bases and ...
Subjective tinnitus is commonly defined as the perception of sound in the absence of an external source. It is an extremely common condition, with prevalence estimates between 10 - 30% worldwide. Despite an increased surge in tinnitus research in recent years, a clear understanding of the neural bases and widely efficacious treatment strategies are still missing. The absence of an objective diagnostic test, lack of a standardized animal model and heterogeneity in humans adds to the challenge of developing a unified tinnitus theory. Additionally, animal and human literature often contradict or do not complement one another. Various theories have been developed based on behavioral, cognitive, computational, and circuit studies in humans and animals, including but not limited to central gain, stochastic resonance, neural synchrony, predictive coding and sensory gating; yet it is not clear how these theories reconcile with one another, nor how they can clearly lead to understand the neural bases of tinnitus or lead to the development of effective treatments options.
We are looking to bridge the gap between animal and human tinnitus research with the current special issue topic. Specifically, how can we relate findings from animal literature to the human condition, and vice versa how can the human condition inform research in animal models? This can be achieved through a variety of means, including but not limited to theory development, behavioral models, electrophysiology and neuroimaging.
We welcome Original Research Articles, Method Articles, Perspectives, Hypotheses & Theories, Review Articles (specifically ones that bring together both animal and human literature).
Keywords:
Tinnitus, animal models, human subjects, theoretical perspectives
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.