As our environment becomes increasingly noisy and the prevalence of hearing-related disorders continues to rise, research on the auditory system has become all the more pressing. Auditory perception is fundamental to human experience, and this topic holds significant importance in contemporary research. Recent breakthroughs in auditory science have propelled our understanding forward, yet various challenges and limitations persist. For example, research on the regeneration of auditory hair cells has not yet overcome technical barriers. Factors such as noise-induced hearing loss, age-related hearing decline, and the need for effective protection strategies underscore the urgency of further exploration of the complexities of auditory functioning and protection.In this Research Topic, we aim to encourage discussions and uncover new findings relating to the three main goals:• to explore the remarkable adaptability and plasticity of the auditory system in response to sensory experiences and environmental changes.• to investigate the various factors contributing to auditory damage, resulting from noise exposure, ototoxic drugs, and genetic predisposition. Unraveling the underlying mechanisms will provide insights into interventions and preventive strategies.• to showcase cutting-edge research on protective measures against auditory damage, encompassing pharmacological interventions, the use of hearing aids, and emerging genetic therapies aimed at preserving and restoring auditory function.Topics of interest include but are not limited to:• Neurobiology of Auditory Development: Related signaling pathways and regulatory mechanisms in auditory neural development process and molecular mechanisms governing the maturation of the auditory system.• Auditory Plasticity Across the Lifespan: The molecular mechanism of activity dependent plasticity in the auditory center which has the investigation into how the auditory system adapts and evolves throughout an individual's life.• Protective Strategies Against Noise/Drug-Induced Damage: Different cell death modes and molecular mechanisms about the noise/drug-induced damage • Genetic and Molecular Therapies for Auditory Restoration: Exploration of the potential of genetic interventions in restoring hearing.
As our environment becomes increasingly noisy and the prevalence of hearing-related disorders continues to rise, research on the auditory system has become all the more pressing. Auditory perception is fundamental to human experience, and this topic holds significant importance in contemporary research. Recent breakthroughs in auditory science have propelled our understanding forward, yet various challenges and limitations persist. For example, research on the regeneration of auditory hair cells has not yet overcome technical barriers. Factors such as noise-induced hearing loss, age-related hearing decline, and the need for effective protection strategies underscore the urgency of further exploration of the complexities of auditory functioning and protection.In this Research Topic, we aim to encourage discussions and uncover new findings relating to the three main goals:• to explore the remarkable adaptability and plasticity of the auditory system in response to sensory experiences and environmental changes.• to investigate the various factors contributing to auditory damage, resulting from noise exposure, ototoxic drugs, and genetic predisposition. Unraveling the underlying mechanisms will provide insights into interventions and preventive strategies.• to showcase cutting-edge research on protective measures against auditory damage, encompassing pharmacological interventions, the use of hearing aids, and emerging genetic therapies aimed at preserving and restoring auditory function.Topics of interest include but are not limited to:• Neurobiology of Auditory Development: Related signaling pathways and regulatory mechanisms in auditory neural development process and molecular mechanisms governing the maturation of the auditory system.• Auditory Plasticity Across the Lifespan: The molecular mechanism of activity dependent plasticity in the auditory center which has the investigation into how the auditory system adapts and evolves throughout an individual's life.• Protective Strategies Against Noise/Drug-Induced Damage: Different cell death modes and molecular mechanisms about the noise/drug-induced damage • Genetic and Molecular Therapies for Auditory Restoration: Exploration of the potential of genetic interventions in restoring hearing.