About this Research Topic

Background

Arrhythmias, ranging from atrial fibrillation to ventricular tachycardia, pose a substantial burden on global healthcare systems. While structural heart disease is a well-established trigger for arrhythmias, emerging research indicates that the autonomic nervous system plays a pivotal role in their initiation, maintenance and progression. The autonomic nervous system's dynamic balance between sympathetic and parasympathetic activity can significantly influence cardiac electrophysiology, making it an intriguing area of investigation.

This special issue builds upon the growing body of evidence suggesting that autonomic dysfunction contributes to arrhythmia development and progression. Recent advances in technology and research methodologies have enabled a deeper exploration of autonomic mechanisms involved in arrhythmogenesis. Additionally, there have been exciting developments in diagnostic tools and novel therapeutic interventions targeting the autonomic nervous system for arrhythmia management.

We would like to address the points below:

Mechanisms: To provide a comprehensive overview of the intricate mechanisms through which the autonomic nervous system influences arrhythmias. Contributions will delve into the molecular, cellular, and physiological aspects of autonomic regulation of cardiac electrophysiology.

Diagnosis: To highlight cutting-edge diagnostic techniques, including advanced imaging modalities, wearable devices, and biomarkers, that allow for precise assessment of autonomic involvement in arrhythmias. These methods hold the potential to revolutionize early detection and risk stratification.

Therapy: To present the latest advancements in therapeutic approaches targeting the autonomic nervous system to prevent, mitigate, or manage arrhythmias. This may encompass neuromodulation techniques, pharmacological interventions, and lifestyle modifications.

The aim of this research topic is to explore the intricate relationship between the autonomic nervous system and arrhythmias, shedding light on the underlying mechanisms, advanced diagnostic techniques, and innovative therapeutic strategies. Arrhythmias significantly affect patients' quality of life and could be life-threatening. A comprehensive understanding of how the autonomic nervous system contributes to arrhythmogenesis is crucial for improving patient care and outcomes.

Finally, this special issue aims to bridge the gap between basic research, clinical practice, and technological innovations in the field of autonomic involvement in arrhythmias. By doing so, it strives to provide a platform for interdisciplinary collaboration and accelerate the translation of scientific discoveries into improved patient care, ultimately enhancing the quality of life for individuals affected by arrhythmias.

Keywords: arrhythmia management, clinical studies, biomarkers, pharmacological interventions

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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