About this Research Topic
Metabolomic disorders, on the other hand, are characterized by abnormal levels or functioning of metabolites. Imbalances in metabolites have been linked to several diseases such as obesity, diabetes, cardiovascular diseases, bone metabolomic disorders, abnormal tumor metabolism, and even mental health disorders. Researchers are actively investigating this area to unravel the underlying mechanisms and identify potential biomarkers for diagnosing or predicting these disorders. Research has shown that the composition and activity of gut microbiota can influence the production and metabolism of various metabolites. For instance, certain bacteria can produce short-chain fatty acids (SCFAs) through the fermentation of dietary fiber. SCFAs have been associated with numerous health benefits including anti-inflammatory effects and regulation of energy metabolism.
The purpose of the Research Topic is to investigate the relationship between microbiota and metabolomic disorders. We aim to understand how the microbiota influences metabolomic disorders, such as obesity, diabetes, cardiovascular diseases, gastrointestinal disorders, bone metabolomic disorders, and abnormal tumor metabolism. By studying this interaction, researchers hope to gain insights into potential therapeutic approaches or interventions that can target the microbiota to prevent or treat metabolomic disorders.
We welcome submissions from diverse backgrounds, including microbiology, metabolomics, nutrition, and clinical sciences, to explore this fascinating topic. Contributions may focus on elucidating specific microbial-metabolite interactions, investigating the impact of dietary interventions on microbiota-metabolite profiles, or exploring novel therapeutic strategies targeting these interactions. By sharing your findings and insights, we can collectively advance our understanding of how microbiota-metabolite interactions contribute to human health and disease.
Keywords: microbiota, metabolism, microbial-metabolite interactions
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