It is well-documented that skeletal muscle is one of the most adaptable tissues in human physiology. Changes can be seen from the molecular to whole muscle level that may also practically facilitate performance enhancement. Thus, a plethora of compounds and other nutritional strategies have been employed to - both directly and indirectly - augment performance metrics spanning muscular strength, aerobic capacity, and even clinical improvements in functional capacity. From the empirically anchored role of creatine monohydrate supplementation to the unsubstantiated products pandered to the masses as the next ergogenic aid, there is no shortage of approaches in this regard.
Therefore, this Research Topic aims to showcase the various means by which skeletal muscle may adapt to ergogenic aids, dietary modifications, and other ancillary practices. We welcome all article categories, including original research, systematic reviews, meta-analyses, narrative reviews, and case reports. All submissions should, however, pertain to skeletal muscle adaptation in response to the broad categories listed above and in the subcategories listed below. Authors are open to discussing data pertaining to both basic mechanisms and/or applied science outcomes.
Potential sub-topics are (not limited to) the cellular mechanisms and practical performance applications of the following on skeletal muscle adaptation:
• Nutraceuticals and other naturally derived compounds (curcumin, phytoecdysteroids, etc.).
• Sports supplements (creatine monohydrate, ß-alanine, etc.).
• Dietary paradigms such as time-restricted feeding, the ketogenic diet, protein-timing, etc.
• General protein metabolism (fractional synthetic rates, protein synthesis-associated target fractional phosphorylation, catabolic targets (E3 ubiquitin ligases, Calpains, etc.), and others.
• Anabolic steroids, SARMs, and other pharmaceutical agents.
• Probiotics, prebiotics, and the various impacts of microbiome composition.
• Other broad exercise physiology strategies and intersections between the aforementioned and otherwise unmentioned topics.
It is well-documented that skeletal muscle is one of the most adaptable tissues in human physiology. Changes can be seen from the molecular to whole muscle level that may also practically facilitate performance enhancement. Thus, a plethora of compounds and other nutritional strategies have been employed to - both directly and indirectly - augment performance metrics spanning muscular strength, aerobic capacity, and even clinical improvements in functional capacity. From the empirically anchored role of creatine monohydrate supplementation to the unsubstantiated products pandered to the masses as the next ergogenic aid, there is no shortage of approaches in this regard.
Therefore, this Research Topic aims to showcase the various means by which skeletal muscle may adapt to ergogenic aids, dietary modifications, and other ancillary practices. We welcome all article categories, including original research, systematic reviews, meta-analyses, narrative reviews, and case reports. All submissions should, however, pertain to skeletal muscle adaptation in response to the broad categories listed above and in the subcategories listed below. Authors are open to discussing data pertaining to both basic mechanisms and/or applied science outcomes.
Potential sub-topics are (not limited to) the cellular mechanisms and practical performance applications of the following on skeletal muscle adaptation:
• Nutraceuticals and other naturally derived compounds (curcumin, phytoecdysteroids, etc.).
• Sports supplements (creatine monohydrate, ß-alanine, etc.).
• Dietary paradigms such as time-restricted feeding, the ketogenic diet, protein-timing, etc.
• General protein metabolism (fractional synthetic rates, protein synthesis-associated target fractional phosphorylation, catabolic targets (E3 ubiquitin ligases, Calpains, etc.), and others.
• Anabolic steroids, SARMs, and other pharmaceutical agents.
• Probiotics, prebiotics, and the various impacts of microbiome composition.
• Other broad exercise physiology strategies and intersections between the aforementioned and otherwise unmentioned topics.
