About this Research Topic
Cardiac rehabilitation doesn’t change the past, but it can be helpful in the improvement of the heart’s future. As a continuum of care for patients with cardiovascular diseases after emergency treatment, it has been shown to not only reduce risk factors of cardiovascular diseases but also provide direct endogenous cardiovascular protection including the improvement of cardiopulmonary capacity and long-term prognosis. However, controversial results of cardiac rehabilitation still exist. The major barriers are lack of evidence-based innovative interventions and evaluation methods. How these promising interventions affects functional and structural remodelling after cardiovascular diseases are not fully understood. In addition, a better mechanistic understanding revealed by novel techniques (e.g., single-cell sequencing combined with RNA sequencing) underlying cardiac rehabilitation is desperately warranted for developing newer and more effective therapeutic strategies.
The Research Topic might discuss the latest update in the field of cardiac rehabilitation in depth and provide evidence-based practical perspectives for facilitating cardiac rehabilitation in clinical context. Specifically, the goal of this Research Topic tends to call for high quality articles involving advances of the clinical applications and underlying molecular mechanisms from bench to bedside and beyond to highlight the innovative insights of cardiac rehabilitation in the prevention, evaluation and treatment of cardiovascular diseases via basic, translational and clinical research.
We hope to receive papers on the following topics:
1) Novel clinical practice in cardiac rehabilitation, for instance in patients treated with mechanical ventilation or extracorporeal membrane oxygenation (ECMO).
2) Protocol tailoring of conventional cardiac rehabilitation including timing, duration, frequency and intensity.
3) Translational studies and newly developed evaluation techniques for cardiac rehabilitation.
4) Threshold mapping of physiological and pathological status with advanced or conventional evaluation parameters on functional prognosis across races.
5) Experimental investigations into advanced mechanisms (e.g., brain-heart axis, gut-heart axis) and functional recovery after cardiovascular diseases.
6) Novel techniques (e.g., single-cell sequencing combined with RNA sequencing) revealing mechanisms underlying cardiac rehabilitation-induced recovery.
7) Innovative methods (e.g., biological or imaging biomarkers) to evaluate functional prognosis after cardiac rehabilitation.
8) Artificial intelligence technique based prediction of long-term functional recovery after cardiovascular diseases, for instance the utilization of sequencing dataset in the prediction of functional recovery.
Keywords: cardiac rehabilitation, functional prognosis, gut-heart axis, single-cell sequencing, biological biomarkers, artificial intelligence technique
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