Editors

Tobias Schuerholz

University Hospital Rostock

Christoph Thiemermann

Queen Mary University of London

Alexandre Mebazaa

Assistance Publique Hopitaux De Paris

Impact

Original Research

13 September 2018

Inhibition of NKCC1 Modulates Alveolar Fluid Clearance and Inflammation in Ischemia-Reperfusion Lung Injury via TRAF6-Mediated Pathways

Chih-Hao Shen

, 5 more and

Kun-Lun Huang

5,667 views

22 citations

Mini Review

26 July 2018

Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5

Lena Heinbockel

, 8 more and

Klaus Brandenburg

15,599 views

66 citations

Review

02 July 2018

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

Russell B. Hawkins

, 9 more and

Lyle L. Moldawer

27,251 views

235 citations

Perspective

26 June 2018

Deterioration of Organ Function As a Hallmark in Sepsis: The Cellular Perspective

Michael Bauer

, 4 more and

Reinhard Wetzker

8,254 views

30 citations

Original Research

25 June 2018

Impaired Cell Viability and Functionality of Hepatocytes After Incubation With Septic Plasma—Results of a Second Prospective Biosensor Study

Martin Sauer

, 8 more and

Gabriele Nöldge-Schomburg

3,762 views

6 citations

Original Research

25 June 2018

Modeling Hemolytic-Uremic Syndrome: In-Depth Characterization of Distinct Murine Models Reflecting Different Features of Human Disease

Sophie Dennhardt

, 12 more and

Sina M. Coldewey

6,579 views

21 citations

Review

21 June 2018

Is There a Role for Hematopoietic Growth Factors During Sepsis?

Benjamin G. Chousterman

and

Marine Arnaud

9,434 views

33 citations

Review

16 May 2018

Immune Modulation by Human Secreted RNases at the Extracellular Space

Lu Lu

, 2 more and

Ester Boix

15,590 views

151 citations

Review

04 May 2018

Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases

Serge Grazioli

and

Jérôme Pugin

16,877 views

339 citations

Original Research

27 April 2018

CD36 Shunts Eicosanoid Metabolism to Repress CD14 Licensed Interleukin-1β Release and Inflammation

Karina F. Zoccal

, 10 more and

Lúcia Helena Faccioli

5,541 views

22 citations

Original Research

25 April 2018

Inflammatory Response of Human Peripheral Blood Mononuclear Cells and Osteoblasts Incubated With Metallic and Ceramic Submicron Particles

Annett Klinder

, 3 more and

Anika Jonitz-Heincke

7,123 views

31 citations

Original Research

24 April 2018

Host Defense Versus Immunosuppression: Unisexual Infection With Male or Female Schistosoma mansoni Differentially Impacts the Immune Response Against Invading Cercariae

Martina Sombetzki

, 6 more and

Emil C. Reisinger

4,511 views

25 citations

Original Research

11 April 2018

High-Mobility Group Box 1-Induced Complement Activation Causes Sterile Inflammation

Sook Young Kim

, 11 more and

Jeon-Soo Shin

8,239 views

58 citations

Original Research

20 March 2018

Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning

Elisabeth Zechendorf

, 13 more and

Lukas Martin

4,294 views

12 citations

Mini Review

26 February 2018

Interaction of the Human Contact System with Pathogens—An Update

Sonja Oehmcke-Hecht

and

Juliane Köhler

10,679 views

54 citations

Original Research

19 February 2018

Glutathione S-Transferase Pi Prevents Sepsis-Related High Mobility Group Box-1 Protein Translocation and Release

Yi Zhou

, 8 more and

Zhimin Yin

5,326 views

15 citations

Review

19 February 2018

Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis

Christopher Geven

, 1 more and

Peter Pickkers

19,515 views

121 citations

Original Research

05 February 2018

The Neurokinin-1 Receptor Contributes to the Early Phase of Lipopolysaccharide-Induced Fever via Stimulation of Peripheral Cyclooxygenase-2 Protein Expression in Mice

Eszter Pakai

, 14 more and

Andras Garami

10,145 views

17 citations

Original Research

05 February 2018

Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs

Stefano Caserta

, 4 more and

Martin J. Llewelyn

14,385 views

54 citations

Original Research

05 January 2018

Intravital Microscopic Evaluation of the Effects of a CXCR2 Antagonist in a Model of Liver Ischemia Reperfusion Injury in Mice

Thiago Henrique Caldeira de Oliveira

, 7 more and

Mauro Martins Teixeira

4,956 views

27 citations

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Mediators and Organ Crosstalk in Sterile and Infectious Inflammation

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