About this Research Topic
Swine virus diseases pose a significant threat to the pig industry due to their highly contagious nature and ability to cause immense harm. Once a pig is infected, the risk extends to the entire farm or even a larger area. In recent years, there has been an emergence and re-emergence of disease pathogens that have been able to overcome existing immune defense mechanisms through continuous recombination and evolution. As a result, current immune prevention and control measures have become ineffective. Notable examples of these diseases include African swine fever virus (ASFV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine epidemic diarrhea virus (PEDV), and porcine pseudorabies virus (PRV). These viruses constantly mutate under various selection pressures, including immunity within the host body and vaccine-induced immunity. Furthermore, with the increase in international trade, the spread of these viruses has become more rapid and extensive. Moreover, it is worth noting that similar virus strains originating from different regions have the potential to undergo recombination, resulting in the emergence of recombinant mutant strains. These mutant strains can pose a challenge to existing immune prevention and control measures, thereby adding complexity to the ongoing efforts in disease prevention and control.
The research scope encompasses several key areas, including genetic evolution, test methods, immune escape mechanisms, protein interactions, and vaccine development.
- Genetic evolution: understanding the changes that occur in genes and genomes of organisms over time.
- Test methods focus on developing and refining various techniques and protocols for conducting experiments and analyzing data.
- Immune escape mechanisms: how pathogens evade the host immune system.
- Protein interaction: the intricate interactions between different proteins within cells or organisms.
- Vaccine development: designing, developing, and evaluating vaccines for the prevention and treatment of infectious diseases.
The research scope encompasses several key areas, including genetic evolution, test methods, immune escape mechanisms, protein interactions, and vaccine development.
- Genetic evolution: understanding the changes that occur in genes and genomes of organisms over time.
- Test methods focus on developing and refining various techniques and protocols for conducting experiments and analyzing data.
- Immune escape mechanisms: how pathogens evade the host immune system.
- Protein interaction: the intricate interactions between different proteins within cells or organisms.
- Vaccine development: designing, developing, and evaluating vaccines for the prevention and treatment of infectious diseases.
Keywords: Porcine viral disease, Genetic evolution, Immune escape mechanism, Vaccine development, Swine virus
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