We are currently facing an obesity pandemic that affects individuals of all age groups, geographic areas, and social status, among others. Thus, it is essential to generate high-quality scientific evidence to better understand this pathology, its risk factors, and its treatments. Several modifiable and non-modifiable risk factors for the development of obesity have been identified. It has been demonstrated that obese patients have an increased risk of acquiring arterial hypertension, diabetes, dyslipidemia, cardiovascular diseases, cancer, and other chronic conditions. In order to take efficient actions to reverse or prevent these complications, it is also crucial to delve into body composition, lean mass, fat, bone mass, and sarcopenia in patients with obesity. In recent months, there have been developments in pharmacological therapies using GLP-1, GIP, and glucagon agonists, which seem to change the rules of the game regarding therapeutic decision-making in these patients worldwide. However, surgical techniques such as sleeve gastrectomy and Roux-en-Y gastric bypass continue to be the most effective and definitive interventions to achieve adequate weight loss in patients with obesity. Despite the pharmacological development, none of the clinical trials have shown that the operated patients reach more than 30% of the total body weight, as with bariatric surgery techniques.Furthermore, it is fundamental to analyze the impact of diverse therapeutic, non-surgical, and non-pharmacological options to address obesity, such as cognitive-behavioral interventions and different types of diets in combination with physical activity.The objective of this intriguing topic (which is open to author proposals) is to involve researchers so they may communicate their latest discoveries in the field of obesity, its risk factors, and therapeutic approaches. The most recent developments based on evidence will be discussed in the following fields: modifiable and non-modifiable risk factors for the development of obesity; aspects of the environment and lifestyle, such as diet, and exercise, as well as sociocultural and financial variables; and pathologies associated with obesity. Comprehending these elements will shed light on the best innovative obesity treatments.We encourage authors to submit their scientific works according to the following categories, narrative and systematic reviews, mini-reviews, original research articles, and clinical cases on the topics listed below, but not limited to:• Modifiable and non-modifiable risk factors for the development of obesity• Body composition and obesity• Innovative treatments in the field of obesity• Clinical approach to patients with extreme obesity
We are currently facing an obesity pandemic that affects individuals of all age groups, geographic areas, and social status, among others. Thus, it is essential to generate high-quality scientific evidence to better understand this pathology, its risk factors, and its treatments. Several modifiable and non-modifiable risk factors for the development of obesity have been identified. It has been demonstrated that obese patients have an increased risk of acquiring arterial hypertension, diabetes, dyslipidemia, cardiovascular diseases, cancer, and other chronic conditions. In order to take efficient actions to reverse or prevent these complications, it is also crucial to delve into body composition, lean mass, fat, bone mass, and sarcopenia in patients with obesity. In recent months, there have been developments in pharmacological therapies using GLP-1, GIP, and glucagon agonists, which seem to change the rules of the game regarding therapeutic decision-making in these patients worldwide. However, surgical techniques such as sleeve gastrectomy and Roux-en-Y gastric bypass continue to be the most effective and definitive interventions to achieve adequate weight loss in patients with obesity. Despite the pharmacological development, none of the clinical trials have shown that the operated patients reach more than 30% of the total body weight, as with bariatric surgery techniques.Furthermore, it is fundamental to analyze the impact of diverse therapeutic, non-surgical, and non-pharmacological options to address obesity, such as cognitive-behavioral interventions and different types of diets in combination with physical activity.The objective of this intriguing topic (which is open to author proposals) is to involve researchers so they may communicate their latest discoveries in the field of obesity, its risk factors, and therapeutic approaches. The most recent developments based on evidence will be discussed in the following fields: modifiable and non-modifiable risk factors for the development of obesity; aspects of the environment and lifestyle, such as diet, and exercise, as well as sociocultural and financial variables; and pathologies associated with obesity. Comprehending these elements will shed light on the best innovative obesity treatments.We encourage authors to submit their scientific works according to the following categories, narrative and systematic reviews, mini-reviews, original research articles, and clinical cases on the topics listed below, but not limited to:• Modifiable and non-modifiable risk factors for the development of obesity• Body composition and obesity• Innovative treatments in the field of obesity• Clinical approach to patients with extreme obesity