About this Research Topic
There is a huge gap in the understanding and application of connective tissue compromise in neurology which often leads to poor localization of patient symptoms and ultimately either misdiagnosis or lack of diagnosis which then further results in non-effective treatment and poor satisfaction for both the patient and the neurologist. Over the past ten years, there has been an increased focus on the neurological manifestations of connective tissue disorders and the associated diagnoses that often present that help explain many of the symptoms of the patients. This increased focus has led to more research and literature on several topics that will help to fill the gap, but more is needed. Along with the increased focus, however, there is increased controversy and the goal of highlighting what is known will hopefully help quell concerns and questions of doubt.
Scope of the collection will include descriptions of the association of connective tissue disorders and neurological symptoms/disease; discussion of specific diagnoses that have a core root within the loss of structural integrity; diagnostic guidelines; controversies in the field; treatment guidelines; and future directions.
Keywords: Connective tissue, collagen, extracellular matrix, Ehlers-Danlos Syndromes, hypermobility
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