The basal position of fish in vertebrate phylogeny makes them very attractive for genomic and functional comparative immunity studies. In mammals, immune cells include monocytes/macrophages, granulocyte and natural killer cells, which are involved in innate immunity, and B and T cells, which are involved in adaptive immunity. These cell groups are also found in fish; however, the adaptive response of fish is commonly delayed compared to mammals and our understanding of the immune cells is still limited compared to mammals. Comparative immunity studies on fish immune cells including monocytes/macrophages, granulocyte, natural killer cells, T and B cells could provide new insights that are basic for understanding the role of the immune molecules in protecting higher animals against pathogens and to design the protecting measures (e.g. vaccination) against the newly emergent diseases.
In this Research Topic, we would like to focus on fish immune cells and gather relevant articles that discuss the origin, evolution, identification, cell receptor screening, intracellular signal transduction, interaction with pathogens and drugs, and mechanism of immune cells. In doing so, we hope to gain a comprehensive understanding of the role of immune cells in the process of fish adapting to their environment and resisting pathogen infection. Additionally, we hope to improve our understanding of fish innate and adaptive immunity, and provide insights into the evolution of immune systems in other species.
We welcome submissions of original research articles, reviews and mini-reviews on the following sub-topics, including but not limited to:
1. Identification of diversity in immune cell populations in fish
2.Susceptibility of immune cell populations to drugs
3.Effect of nutrition on the function of immune cell population
4.Mutual regulation between different immune cell populations
5.Origin and differentiation of immune cells
6.Similarities and differences in immune cell populations among different fish species
7.Immune response of different immune cell populations to different pathogens
8.Receptors and signaling pathways of immune cell populations
The Topic Editors declare no competing interests with regard to the Research Topic subject.
The basal position of fish in vertebrate phylogeny makes them very attractive for genomic and functional comparative immunity studies. In mammals, immune cells include monocytes/macrophages, granulocyte and natural killer cells, which are involved in innate immunity, and B and T cells, which are involved in adaptive immunity. These cell groups are also found in fish; however, the adaptive response of fish is commonly delayed compared to mammals and our understanding of the immune cells is still limited compared to mammals. Comparative immunity studies on fish immune cells including monocytes/macrophages, granulocyte, natural killer cells, T and B cells could provide new insights that are basic for understanding the role of the immune molecules in protecting higher animals against pathogens and to design the protecting measures (e.g. vaccination) against the newly emergent diseases.
In this Research Topic, we would like to focus on fish immune cells and gather relevant articles that discuss the origin, evolution, identification, cell receptor screening, intracellular signal transduction, interaction with pathogens and drugs, and mechanism of immune cells. In doing so, we hope to gain a comprehensive understanding of the role of immune cells in the process of fish adapting to their environment and resisting pathogen infection. Additionally, we hope to improve our understanding of fish innate and adaptive immunity, and provide insights into the evolution of immune systems in other species.
We welcome submissions of original research articles, reviews and mini-reviews on the following sub-topics, including but not limited to:
1. Identification of diversity in immune cell populations in fish
2.Susceptibility of immune cell populations to drugs
3.Effect of nutrition on the function of immune cell population
4.Mutual regulation between different immune cell populations
5.Origin and differentiation of immune cells
6.Similarities and differences in immune cell populations among different fish species
7.Immune response of different immune cell populations to different pathogens
8.Receptors and signaling pathways of immune cell populations
The Topic Editors declare no competing interests with regard to the Research Topic subject.
