About this Research Topic
Endocrine-Related Cancers encompass a wide range of malignancies affecting various endocrine organs, including the adrenal cortex, breast, multiple endocrine neoplasia, neuroendocrine tumors, ovary, prostate, paraganglioma, parathyroid, pheochromocytoma, pituitary, testes, thyroid, and hormone-dependent cancers. Additionally, neoplasias impacting metabolism and energy production, such as bladder, bone, kidney, lung, and head and neck cancers, are also considered within this context.
Cancer is a multifaceted disease influenced by a myriad of factors, including aging, immunological dysregulation, and metabolic alterations. The aging process has been closely associated with an increased incidence of cancer, suggesting a potential link between age-related changes and tumorigenesis. Moreover, emerging evidence highlights the intricate interplay between the immune system, metabolites, and the development of cancer. Understanding the complex relationship between aging, immunology, metabolites, and metabolism in the context of endocrine-related cancers is of utmost importance for advancing cancer research and facilitating the development of effective therapeutic strategies.
This Research Topic aims to explore the role of aging, immunology, metabolites, and metabolism in the context of endocrine-related cancers. Our goal is to uncover new insights into the mechanisms underlying cancer development, progression, and response to treatment. By addressing key questions related to the impact of aging on the immune system and metabolic pathways, we aim to identify novel therapeutic targets and strategies to improve patient outcomes. Recent advances in these fields have paved the way for exciting discoveries, and this Research Topic seeks to build upon these findings to drive further progress in cancer research.
We invite researchers from diverse disciplines, including oncology, immunology, metabolism, and gerontology, to contribute their original research articles, reviews, translational research and perspectives to this Research Topic. Manuscripts should focus on investigating the role of aging, immunology, metabolites, and metabolism in endocrine-related cancers, encompassing both basic and translational research, as well as clinical studies. We encourage submissions that shed light on recent advancements and provide innovative perspectives in this rapidly evolving field.
Potential sub-topics include but are not limited to:
• Aging and Endocrine-Related Cancers: Investigating the impact of aging on the incidence, progression, and treatment response of endocrine-related cancers, including clinical studies examining age-related factors influencing prognosis and therapeutic outcomes.
• Immunological Dysregulation in Endocrine-Related Cancers: Exploring the role of immune system dysfunction in the development and progression of endocrine-related cancers, with a focus on translational research aimed at developing immunotherapeutic strategies.
• Metabolic Alterations and Energy Production in Endocrine-Related Cancers: Understanding the metabolic rewiring and energy production pathways associated with endocrine-related cancers, including clinical studies elucidating the metabolic profiles and potential therapeutic targets.
• Immune-Metabolic Interplay in Endocrine-Related Cancers: Examining the complex interplay between immune responses, metabolites, and metabolism in the context of endocrine-related cancers, with a particular emphasis on translational research investigating the therapeutic modulation of immune-metabolic interactions.
• Therapeutic Strategies Targeting Aging, Immunity, and Metabolism: Highlighting novel therapeutic approaches that target aging-related changes, immune dysregulation, and metabolic alterations in endocrine-related cancers, including clinical studies assessing the efficacy and safety of these interventions in patient populations.
We welcome manuscripts employing various methodologies, including in vitro and in vivo models, clinical studies, omics approaches, and computational analyses. By fostering collaborations and sharing knowledge across disciplines, we aim to unravel the intricate connections between aging, immunology, metabolites, and metabolism in endocrine-related cancers.
Cancer is a multifaceted disease influenced by a myriad of factors, including aging, immunological dysregulation, and metabolic alterations. The aging process has been closely associated with an increased incidence of cancer, suggesting a potential link between age-related changes and tumorigenesis. Moreover, emerging evidence highlights the intricate interplay between the immune system, metabolites, and the development of cancer. Understanding the complex relationship between aging, immunology, metabolites, and metabolism in the context of endocrine-related cancers is of utmost importance for advancing cancer research and facilitating the development of effective therapeutic strategies.
This Research Topic aims to explore the role of aging, immunology, metabolites, and metabolism in the context of endocrine-related cancers. Our goal is to uncover new insights into the mechanisms underlying cancer development, progression, and response to treatment. By addressing key questions related to the impact of aging on the immune system and metabolic pathways, we aim to identify novel therapeutic targets and strategies to improve patient outcomes. Recent advances in these fields have paved the way for exciting discoveries, and this Research Topic seeks to build upon these findings to drive further progress in cancer research.
We invite researchers from diverse disciplines, including oncology, immunology, metabolism, and gerontology, to contribute their original research articles, reviews, translational research and perspectives to this Research Topic. Manuscripts should focus on investigating the role of aging, immunology, metabolites, and metabolism in endocrine-related cancers, encompassing both basic and translational research, as well as clinical studies. We encourage submissions that shed light on recent advancements and provide innovative perspectives in this rapidly evolving field.
Potential sub-topics include but are not limited to:
• Aging and Endocrine-Related Cancers: Investigating the impact of aging on the incidence, progression, and treatment response of endocrine-related cancers, including clinical studies examining age-related factors influencing prognosis and therapeutic outcomes.
• Immunological Dysregulation in Endocrine-Related Cancers: Exploring the role of immune system dysfunction in the development and progression of endocrine-related cancers, with a focus on translational research aimed at developing immunotherapeutic strategies.
• Metabolic Alterations and Energy Production in Endocrine-Related Cancers: Understanding the metabolic rewiring and energy production pathways associated with endocrine-related cancers, including clinical studies elucidating the metabolic profiles and potential therapeutic targets.
• Immune-Metabolic Interplay in Endocrine-Related Cancers: Examining the complex interplay between immune responses, metabolites, and metabolism in the context of endocrine-related cancers, with a particular emphasis on translational research investigating the therapeutic modulation of immune-metabolic interactions.
• Therapeutic Strategies Targeting Aging, Immunity, and Metabolism: Highlighting novel therapeutic approaches that target aging-related changes, immune dysregulation, and metabolic alterations in endocrine-related cancers, including clinical studies assessing the efficacy and safety of these interventions in patient populations.
We welcome manuscripts employing various methodologies, including in vitro and in vivo models, clinical studies, omics approaches, and computational analyses. By fostering collaborations and sharing knowledge across disciplines, we aim to unravel the intricate connections between aging, immunology, metabolites, and metabolism in endocrine-related cancers.
Keywords: Immunology, Immunosenescence, Metabolites, Metabolic pathways, Endocrine system
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
