The peripheral nervous system is composed of peripheral nerves and ganglia that establish a connection between the central nervous system and the periphery to recruit sensory stimuli and convey motor responses. Functionally, it is comprised of both somatic and visceral fibers of either cranial nerves originating from the brainstem or spinal nerves from the spinal cord. Finally, the sensory ganglia, autonomic ganglia, and the enteric nervous system are part of the peripheral nervous system.
The broadening of knowledge on the molecular, histological, anatomical, and functional aspects of the peripheral nervous system allows a more complete understanding of processes such as pathologies and regeneration after nerve damage. This is the basis for the development of innovative strategies in the clinical setting.
Pathologies and injuries of the central nervous system are much more studied than those of the peripheral nervous system, despite the latter being more frequent. Peripheral nerves widely spread throughout the body and are more likely to be injured because of domestic, work-related trauma, or accidents. Nerve lesions are seen also associated with iatrogenic causes or progressive degenerative diseases. Therefore, we believe it is important to investigate the complete aspects of the peripheral nervous system, both in healthy and pathological conditions in order to understand and enhance the inherent repair mechanisms of the peripheral nervous system.
This Research Topic is aimed at collecting high-quality original research and review articles on the peripheral nervous system that highlight the recent advances in this field. Articles may include basic science, pre-clinical and clinical studies. Studies on somatic and autonomic nervous system underlining molecular, histological, anatomical, and functional aspects as well as methodological manuscripts containing innovative techniques for peripheral nervous system analysis are welcome. Both healthy and pathological conditions could be addressed.
The peripheral nervous system is composed of peripheral nerves and ganglia that establish a connection between the central nervous system and the periphery to recruit sensory stimuli and convey motor responses. Functionally, it is comprised of both somatic and visceral fibers of either cranial nerves originating from the brainstem or spinal nerves from the spinal cord. Finally, the sensory ganglia, autonomic ganglia, and the enteric nervous system are part of the peripheral nervous system.
The broadening of knowledge on the molecular, histological, anatomical, and functional aspects of the peripheral nervous system allows a more complete understanding of processes such as pathologies and regeneration after nerve damage. This is the basis for the development of innovative strategies in the clinical setting.
Pathologies and injuries of the central nervous system are much more studied than those of the peripheral nervous system, despite the latter being more frequent. Peripheral nerves widely spread throughout the body and are more likely to be injured because of domestic, work-related trauma, or accidents. Nerve lesions are seen also associated with iatrogenic causes or progressive degenerative diseases. Therefore, we believe it is important to investigate the complete aspects of the peripheral nervous system, both in healthy and pathological conditions in order to understand and enhance the inherent repair mechanisms of the peripheral nervous system.
This Research Topic is aimed at collecting high-quality original research and review articles on the peripheral nervous system that highlight the recent advances in this field. Articles may include basic science, pre-clinical and clinical studies. Studies on somatic and autonomic nervous system underlining molecular, histological, anatomical, and functional aspects as well as methodological manuscripts containing innovative techniques for peripheral nervous system analysis are welcome. Both healthy and pathological conditions could be addressed.
