It has been revealed that inflammation plays an important role in the progression of skin-related diseases, including burn or trauma wounds, diabetes wounds, pressure ulcers, radiation ulcers, keloids, hypertrophic scars, dermatitis, eczema, psoriasis, vitiligo, etc, causing skin tissue to exhibit over-inflammation, lower inflammation, or chronic inflammation. During this process, bacteria invasion, microbiota dysbiosis, or autoimmunity are known as the general initiators to induce the abnormal activity of immune cells and molecules and could change the crosstalk between immune cells and repair cells (or interstitial cells). Therefore, the research deep into the novel mechanisms of inflammation, the new signal pathway of immunity chain responses, or the new relationship between inflammation and repair cells, is of great interest for the design of novel therapies for skin-related diseases.
The goal of this Research Topic is to provide a forum to advance research on the contribution of inflammation to skin wound repair and various skin diseases and explore novel immune-targeted therapies for skin-related diseases.
We encourage contributions of Original Research, Clinical Trials, Reviews, and Commentaries that explore a broad range of topics, including but not limited to:
1. New initiators of inflammation such as special bacterial infection, microbiota imbalance, and autoimmunity defect that participate in the immunity chain response of skin-related diseases.
2. New mechanism of crosstalk between immunity cells(or molecules) and repair cells (or interstitial cells) in skin-related diseases.
3. Novel immunotherapies to treat skin-related diseases including new drug targets, flora therapy, anti-microorganism, adoptive cell therapy, immune checkpoint inhibitors, etc.
4. Immuno-biomarkers that can be identified to diagnose the diseases, or predicate the progression of skin-related diseases.
5. Pre-clinical or clinical evaluation of current immunotherapies on skin-related diseases.
6. Development of in vitro models of skin-related disease with immune components.
It has been revealed that inflammation plays an important role in the progression of skin-related diseases, including burn or trauma wounds, diabetes wounds, pressure ulcers, radiation ulcers, keloids, hypertrophic scars, dermatitis, eczema, psoriasis, vitiligo, etc, causing skin tissue to exhibit over-inflammation, lower inflammation, or chronic inflammation. During this process, bacteria invasion, microbiota dysbiosis, or autoimmunity are known as the general initiators to induce the abnormal activity of immune cells and molecules and could change the crosstalk between immune cells and repair cells (or interstitial cells). Therefore, the research deep into the novel mechanisms of inflammation, the new signal pathway of immunity chain responses, or the new relationship between inflammation and repair cells, is of great interest for the design of novel therapies for skin-related diseases.
The goal of this Research Topic is to provide a forum to advance research on the contribution of inflammation to skin wound repair and various skin diseases and explore novel immune-targeted therapies for skin-related diseases.
We encourage contributions of Original Research, Clinical Trials, Reviews, and Commentaries that explore a broad range of topics, including but not limited to:
1. New initiators of inflammation such as special bacterial infection, microbiota imbalance, and autoimmunity defect that participate in the immunity chain response of skin-related diseases.
2. New mechanism of crosstalk between immunity cells(or molecules) and repair cells (or interstitial cells) in skin-related diseases.
3. Novel immunotherapies to treat skin-related diseases including new drug targets, flora therapy, anti-microorganism, adoptive cell therapy, immune checkpoint inhibitors, etc.
4. Immuno-biomarkers that can be identified to diagnose the diseases, or predicate the progression of skin-related diseases.
5. Pre-clinical or clinical evaluation of current immunotherapies on skin-related diseases.
6. Development of in vitro models of skin-related disease with immune components.
