Novel Pharmacological Targets and Strategies to treat Neglected Global Diseases (NGDs): An LMIC Perspective

Cover image for research topic "Novel Pharmacological Targets and Strategies to treat Neglected Global Diseases (NGDs): An LMIC Perspective"
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Illustrative structures of plant-based nanoparticles used to manage malaria. (A) Top: Plant extract-based metallic NPs coated with phytochemicals. Bottom: essential oil encapsulated in nanocapsule, both for the vector control. (B) Plant virus-based vaccine and antimalarial nanocarriers from mosaic viruses. (C) Nanocarriers encapsulating existing antimalarials or plant extract with antimalarial potential. Structures created with www.BioRender.com.
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Absorption, Distribution, Metabolism, Excretion (ADMET) prediction heat map of natural products (A); and Lipinski rule of five and PAINS, Brenk alerts, Lead likeness (B).
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