In Eva Jablonka and Lamb’s words, epigenetics is one of the four dimensions of evolution. After decades thinking and acting as if the genome determined the absolute fate of any life form in Earth, the relevance of epigenetics for mammalian life, disease and death is now recognized. In fact, assuming similar genomes, lifespan, life style, and risk of diseases, etc. results from a balance between genes and epigenetic traits. The Research Topic aims to show the differences of epigenetic traits between tissues, their physiological relevance and potential to target epigenetic mechanisms in human diseases.
In Eva Jablonka and Lamb’s words, epigenetics is one of the four dimensions of evolution. After decades thinking and acting as if the genome determined the absolute fate of any life form in Earth, the relevance of epigenetics for mammalian life, disease and death is now recognized. In fact, assuming similar genomes, lifespan, life style, and risk of diseases, etc. results from a balance between genes and epigenetic traits. The Research Topic aims to show the differences of epigenetic traits between tissues, their physiological relevance and potential to target epigenetic mechanisms in human diseases.