Treatment of Brain Metastases from Non-Small Cell Lung Cancer: Preclinical, Clinical, and Translational Research

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CASE REPORT

Published on 30 Jan 2025

Case report: A case report and literature review on the efficacy of high-dose aumolertinib combined intrathecal pemetrexed by Ommaya reservoir for EGFR-mutated NSCLC with leptomeningeal metastasis as the initial symptoms

Maoxi Zhong
Li Zhou
Jing Guo
Chuan Chen
Wei Wang
Xiaoping Huang
Yi Liu

doi 10.3389/fonc.2025.1502934

473 views

CASE REPORT

Published on 23 Dec 2024

Penpulimab and Anlotinib in PDL1 high-expression pulmonary giant cell carcinoma with cerebral metastases: case report and review

Minghong Xie
Yunlong Zhao
Xiaohua Hou
Ning Li
Sha Niu
Xinju Xu

doi 10.3389/fonc.2024.1476205

428 views

REVIEW

Published on 29 Oct 2024

Treatment of brain metastases from non-small cell lung cancer: preclinical, clinical, and translational research

Parth J. Sampat
Alyssa Cortese
Alexandra Goodman
Ghanshyam H. Ghelani
Michael D. Mix
Stephen Graziano
Alina Basnet

doi 10.3389/fonc.2024.1411432

871 views

SYSTEMATIC REVIEW

Published on 21 Oct 2024

The benefit and risk of addition of chemotherapy to EGFR tyrosine kinase inhibitors for EGFR-positive non-small cell lung cancer patients with brain metastases: a meta-analysis based on randomized controlled trials

Zhigang Chen
Xiang Fu
Lingping Zhu
Xiurong Wen

doi 10.3389/fonc.2024.1448336

834 views

ORIGINAL RESEARCH

Published on 03 Sep 2024

Impact of lung adenocarcinoma subtypes on survival and timing of brain metastases

Chuyan Zhou
Xiaofang Zhang
Xingyu Yan
Haitao Xie
Hao Tan
Yingqiu Song
Mo Li
Yi Jin
Tianlu Wang

doi 10.3389/fonc.2024.1433505

642 views

ORIGINAL RESEARCH

Published on 27 Aug 2024

Bevacizumab reduces cerebral radiation necrosis due to stereotactic radiotherapy in non-small cell lung cancer patients with brain metastases: an inverse probability of treatment weighting analysis

Jingwei Zhang
Jiayi Yu
Dan Yang
Leilei Jiang
Xin Dong
Zhiyan Liu
Rong Yu
Huiming Yu
Anhui Shi

doi 10.3389/fimmu.2024.1399613

867 views
1 citation

ORIGINAL RESEARCH

Published on 22 May 2024

Clinicopathological characteristics and prognosis of synchronous brain metastases from non-small cell lung cancer compared with metachronous brain metastases

Jing Li
Xiaofang Zhang
Ye Wang
Yi Jin
Yingqiu Song
Tianlu Wang

doi 10.3389/fonc.2024.1400792

601 views

ORIGINAL RESEARCH

Published on 15 Apr 2024

Development and validation of an MRI-Based nomogram to predict the effectiveness of immunotherapy for brain metastasis in patients with non-small cell lung cancer

Junhao Xu
Peiliang Wang
Yikun Li
Xiaonan Shi
Tianwen Yin
Jinming Yu
Feifei Teng

doi 10.3389/fimmu.2024.1373330

1,614 views
3 citations

ORIGINAL RESEARCH

Published on 07 Feb 2024

First-line chemoimmunotherapy and immunotherapy in patients with non-small cell lung cancer and brain metastases: a registry study

Lauren Julia Brown
Victor Khou
Chris Brown
Marliese Alexander
Dasantha Jayamanne
Joe Wei
Lauren Gray
Wei Yen Chan
Samuel Smith
12 more
Benjamin Y. Kong

doi 10.3389/fonc.2024.1305720

1,867 views
4 citations

ORIGINAL RESEARCH

Published on 10 Jan 2024

Cerebrospinal fluid ctDNA testing shows an advantage over plasma ctDNA testing in advanced non-small cell lung cancer patients with brain metastases

Xiaocui Liu
Fengjun Mei
Mei Fang
Yaqiong Jia
Yazhu Zhou
Chenxi Li
Panpan Tian
Chufan Lu
Guangrui Li

doi 10.3389/fonc.2023.1322635

1,274 views
1 citation

ORIGINAL RESEARCH

Published on 07 Nov 2023

Use of comprehensive genomic profiling for biomarker discovery for the management of non-small cell lung cancer brain metastases

Mohammed Abdulhaleem
John C. Hunting
Yuezhu Wang
Margaret R. Smith
Ralph D’ jr. Agostino
Thomas Lycan
Michael K. Farris
James Ververs
Hui-Wen Lo
8 more
Jimmy Ruiz

doi 10.3389/fonc.2023.1214126

1,334 views
1 citation

CASE REPORT

Published on 18 Oct 2023

Successful therapy using high-dose furmonertinib for non-small cell lung cancer with leptomeningeal metastasis: a case report and literature review

Ting Chen
Jie Chen
De-sheng Liu
Yan-ling Shu
Mao-yue Fu
Hai-jun Gou
Kai-jian Lei
Yu-ming Jia

doi 10.3389/fonc.2023.1233198

2,170 views
2 citations

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Thoracic Oncology

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Articles

Case report: A case report and literature review on the efficacy of high-dose aumolertinib combined intrathecal pemetrexed by Ommaya reservoir for EGFR-mutated NSCLC with leptomeningeal metastasis as the initial symptoms

Penpulimab and Anlotinib in PDL1 high-expression pulmonary giant cell carcinoma with cerebral metastases: case report and review

Treatment of brain metastases from non-small cell lung cancer: preclinical, clinical, and translational research

The benefit and risk of addition of chemotherapy to EGFR tyrosine kinase inhibitors for EGFR-positive non-small cell lung cancer patients with brain metastases: a meta-analysis based on randomized controlled trials

Impact of lung adenocarcinoma subtypes on survival and timing of brain metastases

Bevacizumab reduces cerebral radiation necrosis due to stereotactic radiotherapy in non-small cell lung cancer patients with brain metastases: an inverse probability of treatment weighting analysis

Clinicopathological characteristics and prognosis of synchronous brain metastases from non-small cell lung cancer compared with metachronous brain metastases

Development and validation of an MRI-Based nomogram to predict the effectiveness of immunotherapy for brain metastasis in patients with non-small cell lung cancer

First-line chemoimmunotherapy and immunotherapy in patients with non-small cell lung cancer and brain metastases: a registry study

Cerebrospinal fluid ctDNA testing shows an advantage over plasma ctDNA testing in advanced non-small cell lung cancer patients with brain metastases

Use of comprehensive genomic profiling for biomarker discovery for the management of non-small cell lung cancer brain metastases

Successful therapy using high-dose furmonertinib for non-small cell lung cancer with leptomeningeal metastasis: a case report and literature review

Frontiers in Oncology

Thoracic Oncology