Due to the depletion of fossil fuels and the concern of climate change, the production of green chemicals via engineering microbes and bioprocesses has been considered an available way to completely transform the traditional production mode, which will lead to new economic growth and reinvent carbon-based civilization. With the development of synthetic biology, a variety of microbes have been modified as hosts including Escherichia coli, yeast and some filamentous fungi. Coupled with the optimization of bioprocesses, different kinds of biochemicals have been successfully produced by engineered microbes. Although the productivity of partial biochemicals has achieved a preferable level, it still cannot meet the needs of industrial production.
Some limitations need to be further concerned in the production of biochemicals by the engineered microbes such as the high production cost, the excessive by-product accumulation, the low conversion efficiency of substrates, the poor tolerance of hosts and so on. Therefore, more effective strategies should be developed focused on these issues. This Research Topic aims to highlight the findings in the field of biochemical production via engineered microbes and bioprocesses, which will contribute to the promotion of the industrial production of biochemicals.
Topics of interest for this Research Topic include, but are not limited to:
- Biosynthesis of novel chemicals and their reconstruction pathways
- Novel metabolic engineering strategies and products extraction techniques for biochemicals,
- Improvement of the fermentation process,
- Conversion of inexpensive raw materials,
- Analysis of metabolic mechanisms.
This Research Topic welcomes comprehensive reviews, research articles, and short communications on novel findings related to these topics.
Due to the depletion of fossil fuels and the concern of climate change, the production of green chemicals via engineering microbes and bioprocesses has been considered an available way to completely transform the traditional production mode, which will lead to new economic growth and reinvent carbon-based civilization. With the development of synthetic biology, a variety of microbes have been modified as hosts including Escherichia coli, yeast and some filamentous fungi. Coupled with the optimization of bioprocesses, different kinds of biochemicals have been successfully produced by engineered microbes. Although the productivity of partial biochemicals has achieved a preferable level, it still cannot meet the needs of industrial production.
Some limitations need to be further concerned in the production of biochemicals by the engineered microbes such as the high production cost, the excessive by-product accumulation, the low conversion efficiency of substrates, the poor tolerance of hosts and so on. Therefore, more effective strategies should be developed focused on these issues. This Research Topic aims to highlight the findings in the field of biochemical production via engineered microbes and bioprocesses, which will contribute to the promotion of the industrial production of biochemicals.
Topics of interest for this Research Topic include, but are not limited to:
- Biosynthesis of novel chemicals and their reconstruction pathways
- Novel metabolic engineering strategies and products extraction techniques for biochemicals,
- Improvement of the fermentation process,
- Conversion of inexpensive raw materials,
- Analysis of metabolic mechanisms.
This Research Topic welcomes comprehensive reviews, research articles, and short communications on novel findings related to these topics.
