About this Research Topic
Autoimmune and autoinflammatory diseases are increasingly being recognized as an important health challenge with a significant impact on patient’s quality of life. Early diagnosis is a key determinant of the progression and proper management of these diseases. Ongoing research advancements have led to the implementation of omics techniques, such as genomics and metabolomics, to identify disease biomarkers that could serve as potential diagnostic and therapeutic targets. However, their translation to clinical practice is being hampered by the lack of validated and reproducible results. In addition, the unraveling of the aetiopathogenetic mechanisms leading to the onset of these diseases will provide new insights in the prevention, prediction and treatment of autoimmune and autoinflammatory diseases.
The aim of this Research Topic is to bring together recent scientific research on the field of omics application in Autoimmune and Autoinflammatory diseases and contribute to the identification and validation of potential diagnostic and therapeutic targets. In addition, we aim to highlight the role of metabolic networks in the pathogenesis of autoimmune and autoinflammatory diseases and broaden our knowledge on their causes and risk factors. We thus invite investigators to share their valuable research on the areas covered in this Research Topic and contribute to the elucidation of autoimmune and autoinflammatory disease aetiology, identification of potent diagnostic and predictive biomarkers, and the development of tailor-made therapeutic approaches. Special focus areas include Hashimoto’s thyroiditis, psoriasis, ulcerative colitis, Crohn’s disease, atopic dermatitis, rheumatoid arthritis, irritable bowel syndrome, lupus erythematosus, multiple sclerosis, and ankylosing spondylitis. Studies on other autoimmune and autoinflammatory diseases are also welcome.
The scope of this Research Topic will cover the following areas:
• Omics applications in autoimmune and autoinflammatory diseases.
• Immunometabolism of autoimmune and autoinflammatory diseases.
• Computational tools to develop biomarkers for autoimmune and autoinflammatory diseases.
• Metabolic causing factors in autoimmune and autoinflammatory diseases.
• Pharmacological and non-pharmacological targeting of metabolism in autoimmune and autoinflammatory diseases.
The Research Topic will include original articles, reviews, perspectives that focus on the use of omics to better understand the aetiopathogenesis of autoimmune and autoinflammatory diseases and identify new potential biomarkers with predictive, diagnostic and therapeutic value.
Dr. Tsoukalasis the scientific director of Metabolomic medicine and Dr. Sarandi works as a molecular biologist at Metabolomic Medicine. All other Topic Editors declare no competing interests.
The aim of this Research Topic is to bring together recent scientific research on the field of omics application in Autoimmune and Autoinflammatory diseases and contribute to the identification and validation of potential diagnostic and therapeutic targets. In addition, we aim to highlight the role of metabolic networks in the pathogenesis of autoimmune and autoinflammatory diseases and broaden our knowledge on their causes and risk factors. We thus invite investigators to share their valuable research on the areas covered in this Research Topic and contribute to the elucidation of autoimmune and autoinflammatory disease aetiology, identification of potent diagnostic and predictive biomarkers, and the development of tailor-made therapeutic approaches. Special focus areas include Hashimoto’s thyroiditis, psoriasis, ulcerative colitis, Crohn’s disease, atopic dermatitis, rheumatoid arthritis, irritable bowel syndrome, lupus erythematosus, multiple sclerosis, and ankylosing spondylitis. Studies on other autoimmune and autoinflammatory diseases are also welcome.
The scope of this Research Topic will cover the following areas:
• Omics applications in autoimmune and autoinflammatory diseases.
• Immunometabolism of autoimmune and autoinflammatory diseases.
• Computational tools to develop biomarkers for autoimmune and autoinflammatory diseases.
• Metabolic causing factors in autoimmune and autoinflammatory diseases.
• Pharmacological and non-pharmacological targeting of metabolism in autoimmune and autoinflammatory diseases.
The Research Topic will include original articles, reviews, perspectives that focus on the use of omics to better understand the aetiopathogenesis of autoimmune and autoinflammatory diseases and identify new potential biomarkers with predictive, diagnostic and therapeutic value.
Dr. Tsoukalasis the scientific director of Metabolomic medicine and Dr. Sarandi works as a molecular biologist at Metabolomic Medicine. All other Topic Editors declare no competing interests.
Keywords: Autoimmune and autoinflammatory disease, metabolomics, biomarkers, immunometabolism, pathogenesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
