Zoonotic diseases are infections that can be transmitted between people and animals. These infections are caused by microorganisms, such as viruses, bacteria, parasites, and fungi. Patients with zoonotic infections can experience severe and life-threatening illness, whilst others remain asymptomatic. For example, animals can harbor germs asymptomatically for long periods with no apparent impact on their own health. However, some microbes carried by animals can result in human illness, depending on the zoonotic disease. Furthermore, it is widely reported that almost 60% of human diseases are zoonotic, and at least 75% of the pathogens that cause diseases in humans are of zoonotic origin. Currently, most of these diseases are neglected despite having a significant negative impact on global health. Examples include several important and common bacterial zoonoses (such as salmonellosis, tuberculosis, brucellosis, and pasteurellosis), viral zoonoses (such as avian influenza, Ebola virus disease, dengue fever, and zika fever), parasitic zoonoses (such as toxoplasmosis, cryptosporidiosis, giardiasis, and babesiosis), and fungal zoonoses (such as sporotrichosis, cryptococcosis, and aspergillosis). Therefore, through this research topic, we aim to explore the pathogenesis, molecular evolution, transmission dynamics, and host interaction mechanism of zoonotic pathogens, and to provide a platform to showcase innovative research focused on the prevention and control of zoonotic disease.In this Research Topic, we welcome both original articles and reviews on the following subtopics:1. Prevalence, host specificity, transmission dynamics, and epidemiology2. Genomics, transcriptomics, and proteomics 3. Role of zoonotic pathogens in host health and diseases4. Host-pathogen interactions
Zoonotic diseases are infections that can be transmitted between people and animals. These infections are caused by microorganisms, such as viruses, bacteria, parasites, and fungi. Patients with zoonotic infections can experience severe and life-threatening illness, whilst others remain asymptomatic. For example, animals can harbor germs asymptomatically for long periods with no apparent impact on their own health. However, some microbes carried by animals can result in human illness, depending on the zoonotic disease. Furthermore, it is widely reported that almost 60% of human diseases are zoonotic, and at least 75% of the pathogens that cause diseases in humans are of zoonotic origin. Currently, most of these diseases are neglected despite having a significant negative impact on global health. Examples include several important and common bacterial zoonoses (such as salmonellosis, tuberculosis, brucellosis, and pasteurellosis), viral zoonoses (such as avian influenza, Ebola virus disease, dengue fever, and zika fever), parasitic zoonoses (such as toxoplasmosis, cryptosporidiosis, giardiasis, and babesiosis), and fungal zoonoses (such as sporotrichosis, cryptococcosis, and aspergillosis). Therefore, through this research topic, we aim to explore the pathogenesis, molecular evolution, transmission dynamics, and host interaction mechanism of zoonotic pathogens, and to provide a platform to showcase innovative research focused on the prevention and control of zoonotic disease.In this Research Topic, we welcome both original articles and reviews on the following subtopics:1. Prevalence, host specificity, transmission dynamics, and epidemiology2. Genomics, transcriptomics, and proteomics 3. Role of zoonotic pathogens in host health and diseases4. Host-pathogen interactions