Zoonotic Diseases: Epidemiology, Multi-omics, and Host-pathogen interactions

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Editorial

04 October 2024

Editorial: Zoonotic diseases: epidemiology, multi-omics, and host-pathogen interactions

Lei Deng

,

Hong Yin

,

Kevin S. W. Tan

and

Anastasios D. Tsaousis

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Editors

4

Massachusetts General Hospital, Harvard Medical School

Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences

National University of Singapore

Anastasios D. Tsaousis

University of Kent

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Zoonotic diseases are infections that can be transmitted between people and animals. These infections are caused by microorganisms, such as viruses, bacteria, parasites, and fungi. Patients with zoonotic infections can experience severe and life-threatening illness, whilst others remain asymptomatic. For example, animals can harbor germs asymptomatically for long periods with no apparent impact on their own health. However, some microbes carried by animals can result in human illness, depending on the zoonotic disease. Furthermore, it is widely reported that almost 60% of human diseases are zoonotic, and at least 75% of the pathogens that cause diseases in humans are of zoonotic origin.

Currently, most of these diseases are neglected despite having a significant negative impact on global health. Examples include several important and common bacterial zoonoses (such as salmonellosis, tuberculosis, brucellosis, and pasteurellosis), viral zoonoses (such as avian influenza, Ebola virus disease, dengue fever, and zika fever), parasitic zoonoses (such as toxoplasmosis, cryptosporidiosis, giardiasis, and babesiosis), and fungal zoonoses (such as sporotrichosis, cryptococcosis, and aspergillosis). Therefore, through this research topic, we aim to explore the pathogenesis, molecular evolution, transmission dynamics, and host interaction mechanism of zoonotic pathogens, and to provide a platform to showcase innovative research focused on the prevention and control of zoonotic disease.

In this Research Topic, we welcome both original articles and reviews on the following subtopics:

1. Prevalence, host specificity, transmission dynamics, and epidemiology
2. Genomics, transcriptomics, and proteomics
3. Role of zoonotic pathogens in host health and diseases
4. Host-pathogen interactions

Zoonotic diseases are infections that can be transmitted between people and animals. These infections are caused by microorganisms, such as viruses, bacteria, parasites, and fungi. Patients with zoonotic infections can experience severe and life-threatening illness, whilst others remain asymptomatic. For example, animals can harbor germs asymptomatically for long periods with no apparent impact on their own health. However, some microbes carried by animals can result in human illness, depending on the zoonotic disease. Furthermore, it is widely reported that almost 60% of human diseases are zoonotic, and at least 75% of the pathogens that cause diseases in humans are of zoonotic origin.

Currently, most of these diseases are neglected despite having a significant negative impact on global health. Examples include several important and common bacterial zoonoses (such as salmonellosis, tuberculosis, brucellosis, and pasteurellosis), viral zoonoses (such as avian influenza, Ebola virus disease, dengue fever, and zika fever), parasitic zoonoses (such as toxoplasmosis, cryptosporidiosis, giardiasis, and babesiosis), and fungal zoonoses (such as sporotrichosis, cryptococcosis, and aspergillosis). Therefore, through this research topic, we aim to explore the pathogenesis, molecular evolution, transmission dynamics, and host interaction mechanism of zoonotic pathogens, and to provide a platform to showcase innovative research focused on the prevention and control of zoonotic disease.

In this Research Topic, we welcome both original articles and reviews on the following subtopics:

1. Prevalence, host specificity, transmission dynamics, and epidemiology
2. Genomics, transcriptomics, and proteomics
3. Role of zoonotic pathogens in host health and diseases
4. Host-pathogen interactions

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Editors

Massachusetts General Hospital, Harvard Medical School

Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences

National University of Singapore

Anastasios D. Tsaousis

University of Kent

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Published In

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Frontiers in Microbiology

Infectious Agents and Disease

Journal Thumbnail

Frontiers in Medicine

Infectious Agents and Disease

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Frontiers in Public Health

Infectious Agents and Disease

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