Central nervous system (CNS) tumors represent about 20% of pediatric cancer cases worldwide and are the leading cause of cancer-related morbidity and mortality. In low- and middle-income countries, limited data suggests significant disparities in outcomes when compared to high-income countries. Nonetheless, this field is understudied and significant work needs to be done to further elucidate the epidemiology, clinical characteristics, and outcomes of this vulnerable population.
In this Research Topic, we aim to describe recent advances in the biology, clinical, molecular, and health system characteristics of children and adolescents with CNS tumors. We welcome submissions of Original Research or Reviews from local and international investigations on the following topics:
1. Epidemiological studies on incidence, mortality, and outcomes of pediatric CNS tumors in low- and middle-income countries.
2.- Molecular characterization of primary CNS tumors diagnosed and treated in centers in low- and middle-income countries
3. Novel approaches to increase access to care for this vulnerable population.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Central nervous system (CNS) tumors represent about 20% of pediatric cancer cases worldwide and are the leading cause of cancer-related morbidity and mortality. In low- and middle-income countries, limited data suggests significant disparities in outcomes when compared to high-income countries. Nonetheless, this field is understudied and significant work needs to be done to further elucidate the epidemiology, clinical characteristics, and outcomes of this vulnerable population.
In this Research Topic, we aim to describe recent advances in the biology, clinical, molecular, and health system characteristics of children and adolescents with CNS tumors. We welcome submissions of Original Research or Reviews from local and international investigations on the following topics:
1. Epidemiological studies on incidence, mortality, and outcomes of pediatric CNS tumors in low- and middle-income countries.
2.- Molecular characterization of primary CNS tumors diagnosed and treated in centers in low- and middle-income countries
3. Novel approaches to increase access to care for this vulnerable population.
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.