Proper regulation of lipid metabolism and lipid-mediated signal transduction is a major foundation of cellular homeostasis in eukaryotic cells. Derangements in these processes result in a number of human diseases. Moreover, infectious agents co-opt cellular pathways for lipid metabolism and signaling as a root strategy in their pathogenesis program. Understanding the underlying biochemistry is key to effective address of diseases associated with deranged lipid signaling.
The goal is to provide a collection of articles that review the cutting edge of a variety of topics that link the biochemistry of lipid metabolism and signaling with the cell biology of disease . Diseases to be featured will include cancer, viral pathogenesis, lipid signaling in obligate intracellular parasites, and neurodegenerative diseases.
Interest is in a concise and up to date discussion of the structural biology and biochemistry that underlies the cell biology of lipid metabolism/signaling as these relate to human disease and to infectious disease.
Proper regulation of lipid metabolism and lipid-mediated signal transduction is a major foundation of cellular homeostasis in eukaryotic cells. Derangements in these processes result in a number of human diseases. Moreover, infectious agents co-opt cellular pathways for lipid metabolism and signaling as a root strategy in their pathogenesis program. Understanding the underlying biochemistry is key to effective address of diseases associated with deranged lipid signaling.
The goal is to provide a collection of articles that review the cutting edge of a variety of topics that link the biochemistry of lipid metabolism and signaling with the cell biology of disease . Diseases to be featured will include cancer, viral pathogenesis, lipid signaling in obligate intracellular parasites, and neurodegenerative diseases.
Interest is in a concise and up to date discussion of the structural biology and biochemistry that underlies the cell biology of lipid metabolism/signaling as these relate to human disease and to infectious disease.