Pharmacogenomics is an emerging field of pharmacology that has been significantly developed over the last decades. Pharmacogenomics studies how a person's genes affect the response to medications. There are currently several studies with substantial clinical evidence that have resulted in the development of guidelines to optimize pharmacotherapy based on genetics. Therefore, pharmacogenomics could provide meaningful information to clinicians and guide treatment selection and modification in several fields such as cardiovascular diseases, cancer, psychiatry, infectious disease, and pain management. Although there is strong clinical evidence about the utility of pharmacogenomics and several guidelines are available, the universal use of pharmacogenomics in clinical practice is an ongoing challenge. Still, a small number of patients, mainly in large academic medical centers, are treated based on their genotype.
This Research Topic aims to cover recent research trends in pharmacogenomics. Areas to be covered may include, but are not limited to:
- Current trends in pharmacogenomics research
- Clinical pharmacogenomics
- Implementation of pharmacogenomics in clinical practice
- Adoption of pharmacogenomic analysis in clinical laboratories
- Pharmacogenomics in primary care
- Use of pharmacogenomics in special populations
Please note: If patient data are analyzed, a comprehensive description of the patients including sex, age, diagnostic criteria, inclusion and exclusion criteria, disease stage, therapy received, comorbidities as well as additional clinical information and assessment of clinical response/effects should be included. If genetic, proteomics, metabolomics, or other omics data are analyzed, a comprehensive description of the methods and the rationale for the selection of the specific data studied should be provided. Studies related to natural compounds, herbal extracts, or traditional medicine products, are outside the scope of this Research Topic and should instead be submitted to the specialty section Ethnopharmacology.
Topic editor Dr. Apostolos Papachristos is employed by Regeneron Pharmaceuticals. All other Topic Editors declare no competing interests with regard to the Research Topic subject.
Pharmacogenomics is an emerging field of pharmacology that has been significantly developed over the last decades. Pharmacogenomics studies how a person's genes affect the response to medications. There are currently several studies with substantial clinical evidence that have resulted in the development of guidelines to optimize pharmacotherapy based on genetics. Therefore, pharmacogenomics could provide meaningful information to clinicians and guide treatment selection and modification in several fields such as cardiovascular diseases, cancer, psychiatry, infectious disease, and pain management. Although there is strong clinical evidence about the utility of pharmacogenomics and several guidelines are available, the universal use of pharmacogenomics in clinical practice is an ongoing challenge. Still, a small number of patients, mainly in large academic medical centers, are treated based on their genotype.
This Research Topic aims to cover recent research trends in pharmacogenomics. Areas to be covered may include, but are not limited to:
- Current trends in pharmacogenomics research
- Clinical pharmacogenomics
- Implementation of pharmacogenomics in clinical practice
- Adoption of pharmacogenomic analysis in clinical laboratories
- Pharmacogenomics in primary care
- Use of pharmacogenomics in special populations
Please note: If patient data are analyzed, a comprehensive description of the patients including sex, age, diagnostic criteria, inclusion and exclusion criteria, disease stage, therapy received, comorbidities as well as additional clinical information and assessment of clinical response/effects should be included. If genetic, proteomics, metabolomics, or other omics data are analyzed, a comprehensive description of the methods and the rationale for the selection of the specific data studied should be provided. Studies related to natural compounds, herbal extracts, or traditional medicine products, are outside the scope of this Research Topic and should instead be submitted to the specialty section Ethnopharmacology.
Topic editor Dr. Apostolos Papachristos is employed by Regeneron Pharmaceuticals. All other Topic Editors declare no competing interests with regard to the Research Topic subject.