HIV as well as SARS-CoV-2 viral infections produced widespread public health issues. The host's immune system, including both the innate and adaptive immune systems, played an increasingly important role in preventing and controlling viral infection. However, persistent virus infection could activate an excessive immune response, leading to harmful immunological activation, which is a common cause of viral infection death.
How does the HIV/SARS-CoV-2 viral infection alter the immune system network of the host and what factors influence illness development are still largely unclear. Meanwhile, more research into how to strengthen vaccines' protection against HIV/SARS-CoV-2 viral infection is needed. Here, we provide an opportunity for an in-depth discussion on a wide range of host responses to HIV/SARS-CoV-2 viral infections in this Research Topic, including but not limited to innate immune responses, T-cell responses, broadly neutralizing antibody generation, and cross-immunity of vaccines against virus-induced diseases.
Our goal is to provide up-to-date information on the pathogenesis, innate and adaptive immunity, and induction of inflammatory responses during HIV/SARS-CoV-2 viral infection or vaccination to scientists working on immune responses, vaccine development, and antiretroviral therapy.
Original Research, Reviews, Mini-Reviews, Hypothesis and Theory, and Perspective articles on the following (but not limited to) themes in HIV/SARS-CoV-2 research field are invited to be submitted:
- Role of innate antiviral immunity against HIV/SARS-CoV-2
- Broadly neutralizing antibody isolation and the protection mechanism
- Viral escape of innate and adaptive immunity
- Vaccine development and protective mechanisms
- In vitro and in vivo viral studies of immunological treatment
HIV as well as SARS-CoV-2 viral infections produced widespread public health issues. The host's immune system, including both the innate and adaptive immune systems, played an increasingly important role in preventing and controlling viral infection. However, persistent virus infection could activate an excessive immune response, leading to harmful immunological activation, which is a common cause of viral infection death.
How does the HIV/SARS-CoV-2 viral infection alter the immune system network of the host and what factors influence illness development are still largely unclear. Meanwhile, more research into how to strengthen vaccines' protection against HIV/SARS-CoV-2 viral infection is needed. Here, we provide an opportunity for an in-depth discussion on a wide range of host responses to HIV/SARS-CoV-2 viral infections in this Research Topic, including but not limited to innate immune responses, T-cell responses, broadly neutralizing antibody generation, and cross-immunity of vaccines against virus-induced diseases.
Our goal is to provide up-to-date information on the pathogenesis, innate and adaptive immunity, and induction of inflammatory responses during HIV/SARS-CoV-2 viral infection or vaccination to scientists working on immune responses, vaccine development, and antiretroviral therapy.
Original Research, Reviews, Mini-Reviews, Hypothesis and Theory, and Perspective articles on the following (but not limited to) themes in HIV/SARS-CoV-2 research field are invited to be submitted:
- Role of innate antiviral immunity against HIV/SARS-CoV-2
- Broadly neutralizing antibody isolation and the protection mechanism
- Viral escape of innate and adaptive immunity
- Vaccine development and protective mechanisms
- In vitro and in vivo viral studies of immunological treatment