Recent trends in infection biology and control of protozoan parasites

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About this Research Topic

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Background

Understanding the infection biology in naturally or experimentally animals is of paramount importance to control and prevent transmission to humans. Protozoan parasitic diseases have a significant hazard on the individual, national, and the global financial aspects. Protozoan diseases like malaria and trypanosomiasis are the main cause of morbidity and mortality in the parasite world in immunocompetent or compromised individuals. Others like toxoplasmosis, cryptosporidiosis, giardiasis are implicated in serious consequences particularly for immunocompromized people. Similarly in animals, many protozoan diseases can trigger drastic economic losses like cryptosporidiosis and coccidiosis in calves, toxoplasmosis in sheep and swines, neosporosis in pregnant heifers. Tick-borne protozoan diseases such as babesiosis and theileriosis are another group of medical and veterinary importance. The absence of licenced vaccinations and lacking of efficient drugs or the emergence of drug-resistance increase the burden of these diseases globally. Accordingly, researchers are required to perform extra efforts and discover new tactics to solve the current problematic situation seeking the protozoan parasite control.

Innovative insights to control the drastic health hazards and economic losses attributable to protozoan infections are urgently required. Because of the high virulence of various protozoan infections and lacking the potential vaccinations and efficient treatment, the hazards of protozoan infections are expected to increase dramatically. Such hazards will be doubled because of climatic changes and focusing the efforts on COVID and other outbreaks control. Herein, we propose to focus on the adverse effect of protozoan diseases on public health and veterinary sections. Also, novel ideas about issues that matter this field including strategies for establishing accurate diagnostic tool, developing potent vaccines, and discovery of efficient drugs will be targeted. Recent experimental advances, novel solid data, and useful information will be provided to help the relevant research community. Special concerns will be specified to protozoan diseases of zoonotic or veterinary importance because of combined health and economic issues.

We cordially invite researchers to submit their insightful studies on this study topic in the form of original research articles, review articles, brief research reports, case reports, perspective articles, methods, and opinions. These are some potential themes for this research topic, however they are not the only ones:

- Studies on the pathobiology and host-parasite interactions conducted on human or human resources or cells using protozoa of animal origin.

- Novel, impactful and insightful reports on the prevalence, sero- and molecular-epidemiological studies of protozoan parasites in farm, companion, and wild animals.

- The use of gene-editing, recombinant protein, or DNA techniques to characterize virulence factors, new parasite strains, or novel diagnostic antigens.

- The preparation of novel vaccines or the sharing of immunological knowledge to lessen the effects of infection.

- Identification of novel drugs, drug targets or providing solutions for emerging resistance to the common anti-parasitic or acaricides compounds.

Keywords: Pathogenesis, Diagnosis, Vaccine, Protozoa, Drug, Infection

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