Due to enormous structural diversity and chemical variety, natural products (NPs) and NP-based semi-synthetic molecules have recently attracted much interest from the research community. Notably, since 60% of chemotherapeutic drugs come from natural sources, NP-based molecules are reliable sources for drug lead compounds. Pseudo-natural products (PNPs), on the other hand, combine natural product (NP) fragments in inventive ways that are not feasible through biosynthetic pathways. They can also be thought of as non-biogenic fusions of NP-derived elements. Scientists have incorporated the principles of biology-oriented synthesis (BIOS) and fragment-based compound design to develop a novel synthesis that extends beyond the natural chemical realm. Attractively, novel alternative molecular scaffolds, or pseudo-natural products, are created by combining and reconnecting scaffolds from various NPs.
The aim of this Research Topic of "natural products (NPs) and pseudo-natural products (PNPs) against veterinary disease-causing microorganisms" is to underline the most recent discoveries and progress in all fields of veterinary sciences dealing with NPs and PNPs. The primary focus of this article collection will be molecular and biological investigations of NPs and PNPs. It will discuss the creation of novel NPs and PNP-based medicinal agents for the treatment of various veterinary infectious diseases (parasitic, bacterial, viral, fungal, etc.) utilizing the most current methods in pharmacology, biotechnology, and genetic engineering.
We welcome manuscripts from, but are not limited to, the following subtopics:
• Natural products (alkaloids, flavonoids, terpenes, glycosides, phenols, quinones, phenylpropanoids, steroids, and coumarins) and Pseudo-natural products (NP-derived fragments, scaffold hopping) application against veterinary diseases (Parasite, Bacteria, Viruses, Fungi)
• Development of cost-effective NP/PNP drugs against veterinary diseases
• In vitro and In vivo animal studies on veterinary NP/PNP drugs
• Exploration of the mode of action of NP/PNP drugs using various molecular tools (dockings, molecular dynamics, in silico prediction)
Due to enormous structural diversity and chemical variety, natural products (NPs) and NP-based semi-synthetic molecules have recently attracted much interest from the research community. Notably, since 60% of chemotherapeutic drugs come from natural sources, NP-based molecules are reliable sources for drug lead compounds. Pseudo-natural products (PNPs), on the other hand, combine natural product (NP) fragments in inventive ways that are not feasible through biosynthetic pathways. They can also be thought of as non-biogenic fusions of NP-derived elements. Scientists have incorporated the principles of biology-oriented synthesis (BIOS) and fragment-based compound design to develop a novel synthesis that extends beyond the natural chemical realm. Attractively, novel alternative molecular scaffolds, or pseudo-natural products, are created by combining and reconnecting scaffolds from various NPs.
The aim of this Research Topic of "natural products (NPs) and pseudo-natural products (PNPs) against veterinary disease-causing microorganisms" is to underline the most recent discoveries and progress in all fields of veterinary sciences dealing with NPs and PNPs. The primary focus of this article collection will be molecular and biological investigations of NPs and PNPs. It will discuss the creation of novel NPs and PNP-based medicinal agents for the treatment of various veterinary infectious diseases (parasitic, bacterial, viral, fungal, etc.) utilizing the most current methods in pharmacology, biotechnology, and genetic engineering.
We welcome manuscripts from, but are not limited to, the following subtopics:
• Natural products (alkaloids, flavonoids, terpenes, glycosides, phenols, quinones, phenylpropanoids, steroids, and coumarins) and Pseudo-natural products (NP-derived fragments, scaffold hopping) application against veterinary diseases (Parasite, Bacteria, Viruses, Fungi)
• Development of cost-effective NP/PNP drugs against veterinary diseases
• In vitro and In vivo animal studies on veterinary NP/PNP drugs
• Exploration of the mode of action of NP/PNP drugs using various molecular tools (dockings, molecular dynamics, in silico prediction)
