Atherosclerosis is a chronic inflammatory disease of the vascular system, and its clinical manifestations mainly include the deposition of lipoproteins, accumulation of immune cells, and formation of fibrous tissue in the vessel wall. Atherosclerosis is classed as a disease of aging since increasing age is an important risk factor for the development of atherosclerosis. Atherosclerosis may not show clinical symptoms but progresses slowly until a sudden onset of a disease such as a heart attack or stroke occurs. The burden of atherosclerosis-related diseases will further increase due to the aging of the global population, the continued high prevalence, and poor management of risk factors such as hypertension and diabetes.
Considerable progress has been made in our understanding of the pathophysiology of atherosclerosis-related diseases and the underlying mechanisms leading to atherosclerosis-related diseases insult. The lack of success in recent clinical trials has led to dramatic improvements in animal models, focus-driven study designs, and the use of new technologies in the study of atherosclerosis-related diseases. Simultaneously, despite progress in atherosclerosis-related disease management, patient care exerts a substantial impact on families, the healthcare system and the economy. Continuing improvements in treatment and care in the preclinical and clinical stages may play an essential role in treating, rehabilitating, and preventing atherosclerosis-related diseases.
In this Research Topic, we focus on an update on the pathophysiology, epidemiology, prevention, treatment, rehabilitation, and management of atherosclerosis-related diseases, especially affordable and potentially widely applicable for the prevention and treatment of atherosclerosis-related diseases. The variations in atherosclerosis-related disease care across the world are also welcomed. We aim to better understand the atherosclerosis-related disease and provide suggestions for policy makers and healthcare providers to address and reduce the growing burden of atherosclerosis-related diseases in the world.
We welcome original research and review articles related to atherosclerosis-related diseases, from underlying molecular and cellular mechanisms to clinical translational applications.
• Epidemiological characteristics and risk factors of atherosclerosis-related diseases
• Primary and secondary prevention strategies for atherosclerosis-related diseases
• The pathogenesis and pathophysiological process of atherosclerosis-related diseases
• Diagnosis of atherosclerosis-related diseases
• Management of atherosclerosis-related diseases
• Atherosclerosis-related diseases rehabilitation
• Atherosclerosis and bone health, bone metabolism
• Outcomes of patients with atherosclerosis-related diseases
• The pathogenesis, diagnosis and treatment of brain-heart comorbidities
Atherosclerosis is a chronic inflammatory disease of the vascular system, and its clinical manifestations mainly include the deposition of lipoproteins, accumulation of immune cells, and formation of fibrous tissue in the vessel wall. Atherosclerosis is classed as a disease of aging since increasing age is an important risk factor for the development of atherosclerosis. Atherosclerosis may not show clinical symptoms but progresses slowly until a sudden onset of a disease such as a heart attack or stroke occurs. The burden of atherosclerosis-related diseases will further increase due to the aging of the global population, the continued high prevalence, and poor management of risk factors such as hypertension and diabetes.
Considerable progress has been made in our understanding of the pathophysiology of atherosclerosis-related diseases and the underlying mechanisms leading to atherosclerosis-related diseases insult. The lack of success in recent clinical trials has led to dramatic improvements in animal models, focus-driven study designs, and the use of new technologies in the study of atherosclerosis-related diseases. Simultaneously, despite progress in atherosclerosis-related disease management, patient care exerts a substantial impact on families, the healthcare system and the economy. Continuing improvements in treatment and care in the preclinical and clinical stages may play an essential role in treating, rehabilitating, and preventing atherosclerosis-related diseases.
In this Research Topic, we focus on an update on the pathophysiology, epidemiology, prevention, treatment, rehabilitation, and management of atherosclerosis-related diseases, especially affordable and potentially widely applicable for the prevention and treatment of atherosclerosis-related diseases. The variations in atherosclerosis-related disease care across the world are also welcomed. We aim to better understand the atherosclerosis-related disease and provide suggestions for policy makers and healthcare providers to address and reduce the growing burden of atherosclerosis-related diseases in the world.
We welcome original research and review articles related to atherosclerosis-related diseases, from underlying molecular and cellular mechanisms to clinical translational applications.
• Epidemiological characteristics and risk factors of atherosclerosis-related diseases
• Primary and secondary prevention strategies for atherosclerosis-related diseases
• The pathogenesis and pathophysiological process of atherosclerosis-related diseases
• Diagnosis of atherosclerosis-related diseases
• Management of atherosclerosis-related diseases
• Atherosclerosis-related diseases rehabilitation
• Atherosclerosis and bone health, bone metabolism
• Outcomes of patients with atherosclerosis-related diseases
• The pathogenesis, diagnosis and treatment of brain-heart comorbidities