With the relative exception of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, paediatric adrenal disorders are rare diseases, usually with an insidious onset and with relevant comorbidities, needing to be properly addressed at patients’ presentation. Moreover, due to the rarity of these disorders, they are not usually recognized at presentation, leading to a potentially harmful diagnostic delay, and may be not considered by clinicians working in non-specialized centres, with poor expertise in managing rare disorders. Furthermore, pediatric adrenal disorders inevitably develop into adult adrenal disorders, requiring a specific attention during in transitional age, in which a family-centered approach should gradually be switched to a patient-centered approach, with different needs and problems to be addressed.
In this Research Topic, we aim to review rare forms of paediatric adrenal disorders, with insights in pathogenesis, clinical presentation, diagnosis, and treatment, to offer clinicians a fast-approaching, complete guide to these rare disorders, helping improve knowledge in an often-neglected setting.
The Article Collection covers all the rare forms in pediatric adrenal disorders, with the exception of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
For each article, we welcome Review Article, preferentially with a systematic approach, but also narrative reviews will be considered. Case reports with literature review may also be considered. Original studies will be evaluated, but they will not be considered as priority.
The subtopics we are currently considering are:
- Rare Forms of Congenital Adrenal Hyperplasia
- X-linked Adrenoleukodystrophy
- Adrenal Hypoplasia Congenita
- Familial Glucocorticoid Deficiency
- Triple A/Allgrove's Syndrome
- Autoimme Polyglandular Syndromes (Main focus on Type 1)
- Genetic forms of Hypoaldosteronism
- Paediatric Adrenal Cushing's Syndrome
- Paediatric Adrenocortical Tumours (Including Syndromic)
- Paediatric Phaeomocromocytoma and Other Tumours of Adrenal Medulla
- Familial Glucocorticoid Resistance
- Transition to Adulthood in Paediatric Adrenal Disorders
With the relative exception of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, paediatric adrenal disorders are rare diseases, usually with an insidious onset and with relevant comorbidities, needing to be properly addressed at patients’ presentation. Moreover, due to the rarity of these disorders, they are not usually recognized at presentation, leading to a potentially harmful diagnostic delay, and may be not considered by clinicians working in non-specialized centres, with poor expertise in managing rare disorders. Furthermore, pediatric adrenal disorders inevitably develop into adult adrenal disorders, requiring a specific attention during in transitional age, in which a family-centered approach should gradually be switched to a patient-centered approach, with different needs and problems to be addressed.
In this Research Topic, we aim to review rare forms of paediatric adrenal disorders, with insights in pathogenesis, clinical presentation, diagnosis, and treatment, to offer clinicians a fast-approaching, complete guide to these rare disorders, helping improve knowledge in an often-neglected setting.
The Article Collection covers all the rare forms in pediatric adrenal disorders, with the exception of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
For each article, we welcome Review Article, preferentially with a systematic approach, but also narrative reviews will be considered. Case reports with literature review may also be considered. Original studies will be evaluated, but they will not be considered as priority.
The subtopics we are currently considering are:
- Rare Forms of Congenital Adrenal Hyperplasia
- X-linked Adrenoleukodystrophy
- Adrenal Hypoplasia Congenita
- Familial Glucocorticoid Deficiency
- Triple A/Allgrove's Syndrome
- Autoimme Polyglandular Syndromes (Main focus on Type 1)
- Genetic forms of Hypoaldosteronism
- Paediatric Adrenal Cushing's Syndrome
- Paediatric Adrenocortical Tumours (Including Syndromic)
- Paediatric Phaeomocromocytoma and Other Tumours of Adrenal Medulla
- Familial Glucocorticoid Resistance
- Transition to Adulthood in Paediatric Adrenal Disorders
