Traumatic brain injury (TBI) remains one of healthcare's most significant challenges and policy making. TBI could not only lead to long-term functional impairment but also a decrease in quality of life. Lowering the mortality risk and benefitting survivors' living quality remains the target of neurotrauma studies globally. With the advent of novel TBI-related clinical and basic research approaches, diagnostics, therapeutics research, and novel and multidisciplinary methods have emerged. Despite promising progress, no completely effective treatment prevents or minimizes TBI and its related neurological and psychiatric sequelae. Understanding the mechanisms underlying the pathophysiology, treatment progress, and clinically based translational and engineering research on TBI may pave the way for potential treatment targets, diagnostic markers, and preventive methods that ultimately lead to efficacious therapeutic strategies.
This Research Topic aims to disseminate high-quality TBI and related research, especially for the compositive and in-depth study in integration, translation, and multidisciplinary approaches in TBI research, including new technology and research methods in clinical neurology, new findings in neuroendocrinology, neuropathology and new development in neuropharmacology, neurophysiology. This Research Topic is focused on novel developments, current challenges, future perspectives, and especially interdisciplinary research in the field of TBI.
The scope of this Research Topic should be the new progress, technologies, methods, and clinically relevant achievements in translational research of TBI. Review, Meta-analysis or Systematic Review, and other related studies focused on neurotrauma, and its related diseases are welcome. Topics include but are not limited to the following：
- Clinical translational research on prevention, diagnosis, and treatment of TBI, clinical trials, or retrospective analysis of novel therapeutic methods related to TBI
- Molecular mechanisms of TBI, advanced neuroimaging features to guide treatment and prognosis, validation of high-yield and emerging new biomarkers, evaluation and prediction of trajectories of recovery, and exploration of solutions to health disparities
- Development of medical bioengineering, biomechanical models, and medical robotics in TBI
- Mathematics and calculation model for prediction of mTBI and forensic expertise
- Artificial intelligence, medical big data analysis, imaging genomics, radiomics, proteomics, metabolomics intelligent early diagnosis, scientometrics, and multiomics analysis of TBI
- Research and development of new drugs in TBI as well as mechanisms of immunology and pharmacology for prevention and treatment of TBI
- Alternative and complementary therapies and intervention methods and occupational protection of TBI as well as related research methodologies
Traumatic brain injury (TBI) remains one of healthcare's most significant challenges and policy making. TBI could not only lead to long-term functional impairment but also a decrease in quality of life. Lowering the mortality risk and benefitting survivors' living quality remains the target of neurotrauma studies globally. With the advent of novel TBI-related clinical and basic research approaches, diagnostics, therapeutics research, and novel and multidisciplinary methods have emerged. Despite promising progress, no completely effective treatment prevents or minimizes TBI and its related neurological and psychiatric sequelae. Understanding the mechanisms underlying the pathophysiology, treatment progress, and clinically based translational and engineering research on TBI may pave the way for potential treatment targets, diagnostic markers, and preventive methods that ultimately lead to efficacious therapeutic strategies.
This Research Topic aims to disseminate high-quality TBI and related research, especially for the compositive and in-depth study in integration, translation, and multidisciplinary approaches in TBI research, including new technology and research methods in clinical neurology, new findings in neuroendocrinology, neuropathology and new development in neuropharmacology, neurophysiology. This Research Topic is focused on novel developments, current challenges, future perspectives, and especially interdisciplinary research in the field of TBI.
The scope of this Research Topic should be the new progress, technologies, methods, and clinically relevant achievements in translational research of TBI. Review, Meta-analysis or Systematic Review, and other related studies focused on neurotrauma, and its related diseases are welcome. Topics include but are not limited to the following：
- Clinical translational research on prevention, diagnosis, and treatment of TBI, clinical trials, or retrospective analysis of novel therapeutic methods related to TBI
- Molecular mechanisms of TBI, advanced neuroimaging features to guide treatment and prognosis, validation of high-yield and emerging new biomarkers, evaluation and prediction of trajectories of recovery, and exploration of solutions to health disparities
- Development of medical bioengineering, biomechanical models, and medical robotics in TBI
- Mathematics and calculation model for prediction of mTBI and forensic expertise
- Artificial intelligence, medical big data analysis, imaging genomics, radiomics, proteomics, metabolomics intelligent early diagnosis, scientometrics, and multiomics analysis of TBI
- Research and development of new drugs in TBI as well as mechanisms of immunology and pharmacology for prevention and treatment of TBI
- Alternative and complementary therapies and intervention methods and occupational protection of TBI as well as related research methodologies
