Chronic diseases - such as cancer, diabetes, neurodegenerative diseases, bone diseases, parkinsonism, and hypertension, are the leading causes of disability and death in the world. Many chronic diseases are linked to lifestyle choices and dietary habits. For example, balanced nutrition and natural food intake have been proven to reduce chronic diseases and the death rate. The healthy function of food-derived bioactive compounds is gradually recognized. Among them, polyphenols show potential antioxidant, anticancer, hypotensive, osteogenic, and anti-inflammatory effects and are considered functional nutraceuticals in preventing chronic diseases. On the other hand, research has also revealed that the functional qualities of food-derived components are related to processing, preservation, and digestion procedure. In addition, food-derived polyphenols can be metabolized via different pathways and eventually absorbed in the body to exert their efficacy. Today, we are still at the beginning of the search to identify and collect functional components in natural foods and to investigate their potential effects.
This research topic aims to gather the latest research that uncovers food-derived polyphenols, which can improve physical function and even prevent chronic diseases. The development of differentiated capture strategies for food components and the elaboration of their changes in the preservation or diet will lay the foundation for the in-depth utilization of functional foods.
• Novel emergent separation/extraction approaches of polyphenols from foods, e.g., novel ionic liquid/deep eutectic solvent extraction, determine the absorption rate of polyphenols by different extraction methods;
• Efficacy evaluation of polyphenols during food processing, preservation, and in-vivo/in-vitro digestive metabolites;
• Absorption and metabolism of food-derived polyphenols in chronic diseases cell/animal models, including cancer, diabetes, neurodegenerative diseases, bone diseases, parkinsonism and hypertension;
• Nutritional or medical studies in cell/animal models or human cohorts by using proteomics, lipidomics, and genomics techniques to discover the beneficial mechanism of bioactive compounds.
Chronic diseases - such as cancer, diabetes, neurodegenerative diseases, bone diseases, parkinsonism, and hypertension, are the leading causes of disability and death in the world. Many chronic diseases are linked to lifestyle choices and dietary habits. For example, balanced nutrition and natural food intake have been proven to reduce chronic diseases and the death rate. The healthy function of food-derived bioactive compounds is gradually recognized. Among them, polyphenols show potential antioxidant, anticancer, hypotensive, osteogenic, and anti-inflammatory effects and are considered functional nutraceuticals in preventing chronic diseases. On the other hand, research has also revealed that the functional qualities of food-derived components are related to processing, preservation, and digestion procedure. In addition, food-derived polyphenols can be metabolized via different pathways and eventually absorbed in the body to exert their efficacy. Today, we are still at the beginning of the search to identify and collect functional components in natural foods and to investigate their potential effects.
This research topic aims to gather the latest research that uncovers food-derived polyphenols, which can improve physical function and even prevent chronic diseases. The development of differentiated capture strategies for food components and the elaboration of their changes in the preservation or diet will lay the foundation for the in-depth utilization of functional foods.
• Novel emergent separation/extraction approaches of polyphenols from foods, e.g., novel ionic liquid/deep eutectic solvent extraction, determine the absorption rate of polyphenols by different extraction methods;
• Efficacy evaluation of polyphenols during food processing, preservation, and in-vivo/in-vitro digestive metabolites;
• Absorption and metabolism of food-derived polyphenols in chronic diseases cell/animal models, including cancer, diabetes, neurodegenerative diseases, bone diseases, parkinsonism and hypertension;
• Nutritional or medical studies in cell/animal models or human cohorts by using proteomics, lipidomics, and genomics techniques to discover the beneficial mechanism of bioactive compounds.
