Morphine, extracted/isolated from the opium poppy, was the first plant-derived natural product, which was first reported in 1806 and marked as the beginning of plant metabolites research. In the following 200 years, many specific metabolites with significant bio-activity, such as quinine, artemisinin, and paclitaxel, were discovered in plant-derived medicines and have been used for treating human diseases. The extracts of plants or their metabolites have contributed significantly to human health, particularly in the treatment of chronic diseases such as diabetes, hypertension, and obesity. Nowadays, medicinal plants and their metabolites are increasingly favored by researchers and pharmaceutical companies to be developed as new dietary supplements and pharmaceuticals. Therefore, screening and identification of novel active metabolites or lead compounds from plant-derived medicines for human disease treatment have become a popular research area.
This Research Topic aims to gain novel insight into the new technologies/analytical methods for phytochemical analysis, new metabolites with significant biological activity, efficient isolation methods, and the structural modifications, total/semi-synthesis, activity evaluation, and biosynthesis pathways of plant-derived metabolites. Recently, the great success of herbal medicine in controlling the spread of COVID-19 has gained lots of attention in the study of natural products from plant-derived medicines. Therefore, articles on anti-SARS-CoV-2 virus/anti-virus of plant-derived metabolites are highly encouraged.
We welcome submissions of different types of manuscripts, including original research papers, reviews, and methods, including but not limited to:
1. New strategy for analysis of the metabolites in plant-derived medicines;
2. Isolation, identification, biological activity evaluation and functional mechanisms of novel metabolites of plant-derived medicines;
3. Mining the anti-virus of the plant-derived metabolites, especially anti-SARS-CoV-2 virus (COVID-19)
4. Structural modification and biological evaluation of specialized plant-derived metabolites;
5. Biosynthesis pathways of phytochemical metabolites and their regulatory mechanisms.
Morphine, extracted/isolated from the opium poppy, was the first plant-derived natural product, which was first reported in 1806 and marked as the beginning of plant metabolites research. In the following 200 years, many specific metabolites with significant bio-activity, such as quinine, artemisinin, and paclitaxel, were discovered in plant-derived medicines and have been used for treating human diseases. The extracts of plants or their metabolites have contributed significantly to human health, particularly in the treatment of chronic diseases such as diabetes, hypertension, and obesity. Nowadays, medicinal plants and their metabolites are increasingly favored by researchers and pharmaceutical companies to be developed as new dietary supplements and pharmaceuticals. Therefore, screening and identification of novel active metabolites or lead compounds from plant-derived medicines for human disease treatment have become a popular research area.
This Research Topic aims to gain novel insight into the new technologies/analytical methods for phytochemical analysis, new metabolites with significant biological activity, efficient isolation methods, and the structural modifications, total/semi-synthesis, activity evaluation, and biosynthesis pathways of plant-derived metabolites. Recently, the great success of herbal medicine in controlling the spread of COVID-19 has gained lots of attention in the study of natural products from plant-derived medicines. Therefore, articles on anti-SARS-CoV-2 virus/anti-virus of plant-derived metabolites are highly encouraged.
We welcome submissions of different types of manuscripts, including original research papers, reviews, and methods, including but not limited to:
1. New strategy for analysis of the metabolites in plant-derived medicines;
2. Isolation, identification, biological activity evaluation and functional mechanisms of novel metabolites of plant-derived medicines;
3. Mining the anti-virus of the plant-derived metabolites, especially anti-SARS-CoV-2 virus (COVID-19)
4. Structural modification and biological evaluation of specialized plant-derived metabolites;
5. Biosynthesis pathways of phytochemical metabolites and their regulatory mechanisms.