At present, there are five main viruses that cause viral hepatitis, including hepatitis A, B, C, D and E. Except for the hepatitis B virus is a DNA virus, the rest are RNA viruses. The five kinds of hepatitis viruses are different in the transmission route and the key population. Early diagnosis and prognosis of hepatitis infection are very important for effective treatment and nursing. The key to addressing viral hepatitis is to develop new therapeutic targets by studying the molecular pathogenic mechanisms of the pathogen-host interactions. This could further enhance the capacity of crucial technologies for the diagnosis and treatment of viral hepatitis in the world.
Hepatitis viruses develop multiple strategies in the long-term evolution to facilitate their proliferation. These strategies include suppressing the induction of innate immunity and modulating the cellular metabolic response of the host, etc. In recent years, more and more attention has been paid to the pathogenic mechanism of hepatitis viruses affecting host immune and non-immune cells. Novel strategies for the diagnosis and treatment of hepatitis infection have been developed by exploring new pathogenic targets. Studying the role of pathogen-derived or released molecules in the pathogenesis of enterohepatic circulation-mediated disease from the perspective of pathogen-host interactions is of great importance for the prevention, control, and treatment of viral hepatitis.
The goal of this Research Topic is to collate articles related to the pathogen-host interaction in the occurrence and development of viral hepatitis. We encourage interested investigators to submit case reports, reviews and original research based on cell models, animal models, human samples and clinical cases aiming to promote the research progress of viral hepatitis.
We welcome submissions of Original Research, Review, Mini Review, Hypothesis and Theory, focusing on the following aspects:
(1) The molecular mechanisms of pathogen-host interaction in viral hepatitis
(2) Novel diagnostic modalities of viral hepatitis, including screening of prognostic markers and the use of machine deep learning to build a severe early warning system
(3) Multi-omics of viral hepatitis, including proteomics, metabolomics, and transcriptomics
(4) Host metabolic mechanism and probiotic therapy in viral hepatitis
At present, there are five main viruses that cause viral hepatitis, including hepatitis A, B, C, D and E. Except for the hepatitis B virus is a DNA virus, the rest are RNA viruses. The five kinds of hepatitis viruses are different in the transmission route and the key population. Early diagnosis and prognosis of hepatitis infection are very important for effective treatment and nursing. The key to addressing viral hepatitis is to develop new therapeutic targets by studying the molecular pathogenic mechanisms of the pathogen-host interactions. This could further enhance the capacity of crucial technologies for the diagnosis and treatment of viral hepatitis in the world.
Hepatitis viruses develop multiple strategies in the long-term evolution to facilitate their proliferation. These strategies include suppressing the induction of innate immunity and modulating the cellular metabolic response of the host, etc. In recent years, more and more attention has been paid to the pathogenic mechanism of hepatitis viruses affecting host immune and non-immune cells. Novel strategies for the diagnosis and treatment of hepatitis infection have been developed by exploring new pathogenic targets. Studying the role of pathogen-derived or released molecules in the pathogenesis of enterohepatic circulation-mediated disease from the perspective of pathogen-host interactions is of great importance for the prevention, control, and treatment of viral hepatitis.
The goal of this Research Topic is to collate articles related to the pathogen-host interaction in the occurrence and development of viral hepatitis. We encourage interested investigators to submit case reports, reviews and original research based on cell models, animal models, human samples and clinical cases aiming to promote the research progress of viral hepatitis.
We welcome submissions of Original Research, Review, Mini Review, Hypothesis and Theory, focusing on the following aspects:
(1) The molecular mechanisms of pathogen-host interaction in viral hepatitis
(2) Novel diagnostic modalities of viral hepatitis, including screening of prognostic markers and the use of machine deep learning to build a severe early warning system
(3) Multi-omics of viral hepatitis, including proteomics, metabolomics, and transcriptomics
(4) Host metabolic mechanism and probiotic therapy in viral hepatitis