Gastric cancer is the fifth most common malignancy and the third leading cause of cancer-related death worldwide. The resection of at least two-thirds of the stomach with a D2 lymph node dissection was considered the standard procedure for gastric cancer. However, short-term and long-term postgastrectomy dysfunction is a problem of standard gastrectomy, including postprandial symptoms, diarrhea, weight loss, and malabsorption, resulting in poor quality of life. To improve postoperative gastrectomy dysfunction, various types of function-preserving or limited surgery have been proposed, including pylorus-preserving gastrectomy (PPG), vagus nerve-preserving gastrectomy, and proximal gastrectomy (PG). Besides, with advances in the techniques and instruments of endoscopic resection, the indications of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have expanded, thus leading to the blurred boundary between surgery and endoscopic resection. Meanwhile, new approaches are emerging such as the combination of laparoscopy with endoscopy for early gastric cancer treatment.
Though function-preserving gastric cancer surgery is performed in many centers, some surgeons are unwilling to perform function-preserving surgery due to the fear of the radical effect of the procedure, and high-quality randomized controlled trials presented so far are rare. Meanwhile, the underlying mechanisms are needed to be further revealed. Therefore, there is a great need to further study these techniques.
The goal of this research topic is to assemble reports from centers where function-preserving gastric cancer surgery has been applied and to present novel techniques as well as studies on the safety and effectiveness of the approaches for function-preserving gastric cancer surgery. Besides, the studies on the mechanism of function-preserving gastric cancer surgery, such as the nerves, hormones, peptides, and the signal pathway that are involved are encouraged. We also encourage the techniques performed by the cooperation of gastrointestinal surgery specialists with endoscopists.
We welcome the submissions of review, mini-review, and original research articles in, but not limited to, the following topics:
1) Prospective and retrospective clinical trials
2) New techniques for endoscopic surgery of early gastric cancer
3) Current updates in approaches for function-preserving gastric cancer surgery
4) The mechanisms underlying the function-preserving gastric cancer surgery
5) The proposed signaling pathway that involved in function-preserving gastric cancer surgery
Gastric cancer is the fifth most common malignancy and the third leading cause of cancer-related death worldwide. The resection of at least two-thirds of the stomach with a D2 lymph node dissection was considered the standard procedure for gastric cancer. However, short-term and long-term postgastrectomy dysfunction is a problem of standard gastrectomy, including postprandial symptoms, diarrhea, weight loss, and malabsorption, resulting in poor quality of life. To improve postoperative gastrectomy dysfunction, various types of function-preserving or limited surgery have been proposed, including pylorus-preserving gastrectomy (PPG), vagus nerve-preserving gastrectomy, and proximal gastrectomy (PG). Besides, with advances in the techniques and instruments of endoscopic resection, the indications of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have expanded, thus leading to the blurred boundary between surgery and endoscopic resection. Meanwhile, new approaches are emerging such as the combination of laparoscopy with endoscopy for early gastric cancer treatment.
Though function-preserving gastric cancer surgery is performed in many centers, some surgeons are unwilling to perform function-preserving surgery due to the fear of the radical effect of the procedure, and high-quality randomized controlled trials presented so far are rare. Meanwhile, the underlying mechanisms are needed to be further revealed. Therefore, there is a great need to further study these techniques.
The goal of this research topic is to assemble reports from centers where function-preserving gastric cancer surgery has been applied and to present novel techniques as well as studies on the safety and effectiveness of the approaches for function-preserving gastric cancer surgery. Besides, the studies on the mechanism of function-preserving gastric cancer surgery, such as the nerves, hormones, peptides, and the signal pathway that are involved are encouraged. We also encourage the techniques performed by the cooperation of gastrointestinal surgery specialists with endoscopists.
We welcome the submissions of review, mini-review, and original research articles in, but not limited to, the following topics:
1) Prospective and retrospective clinical trials
2) New techniques for endoscopic surgery of early gastric cancer
3) Current updates in approaches for function-preserving gastric cancer surgery
4) The mechanisms underlying the function-preserving gastric cancer surgery
5) The proposed signaling pathway that involved in function-preserving gastric cancer surgery