It is now recognized that host diseases can be caused by an imbalance among (polymicrobial) pathogen(s), host, gut microbiota, and survival conditions. In addition, the pathogen–one disease paradigm is often insufficient to explain many diseases. Under these scenarios, it is critical to uncover factors that disrupt the interactions among polymicrobial pathogens in, and immediately surrounding, a host, together with the gut microbiome, associated environments, and subsequent diseases over time.
The underlying ecological and molecular mechanisms governing the interplay among Environments-Pathogens-The gut microbiota and host disease present a more holistic and realistic concept for exploring the causal agents (driving biotic and abiotic factors, polymicrobial pathogens) and mechanisms over disease progression, which in turn guides us to manage and diagnose diseases.
This Research Topic focuses on clarifying the interrelationships among Environments-Pathogens-The gut microbiota and host diseases in animals and humans. Subtopics include, but are not limited to, the following:
(1) Exploring the underlying mechanisms governing the interrelationships among Environments-Pathogens-The gut microbiota and host diseases from a molecular and ecological perspective
(2) Identifying and validating causative relationships between polymicrobial pathogens and host diseases progression
(3) Establishing approaches for diagnosing the incidence and/or outcome of diseases, especially at the early (“subclinical”) stages, and biocontrol strategies for preventing host diseases.
The types of manuscripts can be Original Research, Review or Mini Review, Methods, Opinion, and Perspective.
Please note that Systems Microbiology does not consider descriptive studies that are solely based on amplicon (e.g., 16S rRNA) profiles, unless they are accompanied by a clear hypothesis and experimentation, and provide insight into the microbiological system or process being studied.
It is now recognized that host diseases can be caused by an imbalance among (polymicrobial) pathogen(s), host, gut microbiota, and survival conditions. In addition, the pathogen–one disease paradigm is often insufficient to explain many diseases. Under these scenarios, it is critical to uncover factors that disrupt the interactions among polymicrobial pathogens in, and immediately surrounding, a host, together with the gut microbiome, associated environments, and subsequent diseases over time.
The underlying ecological and molecular mechanisms governing the interplay among Environments-Pathogens-The gut microbiota and host disease present a more holistic and realistic concept for exploring the causal agents (driving biotic and abiotic factors, polymicrobial pathogens) and mechanisms over disease progression, which in turn guides us to manage and diagnose diseases.
This Research Topic focuses on clarifying the interrelationships among Environments-Pathogens-The gut microbiota and host diseases in animals and humans. Subtopics include, but are not limited to, the following:
(1) Exploring the underlying mechanisms governing the interrelationships among Environments-Pathogens-The gut microbiota and host diseases from a molecular and ecological perspective
(2) Identifying and validating causative relationships between polymicrobial pathogens and host diseases progression
(3) Establishing approaches for diagnosing the incidence and/or outcome of diseases, especially at the early (“subclinical”) stages, and biocontrol strategies for preventing host diseases.
The types of manuscripts can be Original Research, Review or Mini Review, Methods, Opinion, and Perspective.
Please note that Systems Microbiology does not consider descriptive studies that are solely based on amplicon (e.g., 16S rRNA) profiles, unless they are accompanied by a clear hypothesis and experimentation, and provide insight into the microbiological system or process being studied.