Inflammatory and oxidative reactions are required biological responses involved in the defense against infection and injury, which are associated with different diseases. The normal inflammatory response has been found that it can promote tissue remodel and recovery. However, excess inflammatory reactions resulting from environmental and genetic factors will lead to chronic inflammatory disease.
Currently, extensive efforts have been devoted to preventing and modulating inflammation diseases, especially biomaterials. Taking advantage of their bioactive features, a large number of novel biomaterials, including hydrogel, nanoparticle, and nanomembrane, have been designed to cope with dramatically increased inflammation diseases. Although biomaterials possess great potential against inflammatory diseases, their impact on clinical practice is still limited and their underlying mechanisms remain to be understood.
The research topic concentrates on the application of anti-inflammatory biomaterials in the prevention and therapy of inflammation diseases, with an emphasis on the investigation of underlying mechanisms of biomaterials. Biomaterials with definite anti-inflammation have been applied to depress excess inflammatory response and show great potential in the prevention and therapy of inflammatory diseases, representing an effective and promising therapeutic strategy for inflammatory diseases. For example, biomaterials composed of natural bioactive compounds could enhance the anti-inflammatory effect of compounds by targeting inflammatory sites or extending the retention time. Despite the therapy’s effect on inflammatory diseases, biomaterials also can prevent pathological adhesion by depressing inflammatory reactions. Furthermore, biomaterials could establish the inflammation balance, but how the biomaterials lead to inflammation balance is still unknown. Investigation of inflammatory response mechanisms could aid the development of novel therapeutic strategies. Therefore, our goal is to encourage scientists to share their studies about the prevention and modulation of inflammatory diseases with biomaterials.
With this research topic, we also aim to gather together frontier research on biomaterials to get a better understanding of the application of anti-inflammatory biomaterials. Therefore, this topic hopes to include preparing novel biomaterials, constructing new drug carrier systems, and investigating underlying anti-inflammatory mechanisms of biomaterials. We welcome submissions in the form of original research, reviews, and comments, including but not limited to the following subtopics:
• The novel preparation method of biomaterial composed of natural bioactive compounds
• The discovery and development of biomaterials-assisted drug delivery strategies
• Investigation of anti-inflammatory mechanisms of biomaterials
• Novel application of biomaterials to inflammation diseases
• In-vitro/ in-vivo evaluation of antioxidant and anti-inflammatory activities of biomaterials
Inflammatory and oxidative reactions are required biological responses involved in the defense against infection and injury, which are associated with different diseases. The normal inflammatory response has been found that it can promote tissue remodel and recovery. However, excess inflammatory reactions resulting from environmental and genetic factors will lead to chronic inflammatory disease.
Currently, extensive efforts have been devoted to preventing and modulating inflammation diseases, especially biomaterials. Taking advantage of their bioactive features, a large number of novel biomaterials, including hydrogel, nanoparticle, and nanomembrane, have been designed to cope with dramatically increased inflammation diseases. Although biomaterials possess great potential against inflammatory diseases, their impact on clinical practice is still limited and their underlying mechanisms remain to be understood.
The research topic concentrates on the application of anti-inflammatory biomaterials in the prevention and therapy of inflammation diseases, with an emphasis on the investigation of underlying mechanisms of biomaterials. Biomaterials with definite anti-inflammation have been applied to depress excess inflammatory response and show great potential in the prevention and therapy of inflammatory diseases, representing an effective and promising therapeutic strategy for inflammatory diseases. For example, biomaterials composed of natural bioactive compounds could enhance the anti-inflammatory effect of compounds by targeting inflammatory sites or extending the retention time. Despite the therapy’s effect on inflammatory diseases, biomaterials also can prevent pathological adhesion by depressing inflammatory reactions. Furthermore, biomaterials could establish the inflammation balance, but how the biomaterials lead to inflammation balance is still unknown. Investigation of inflammatory response mechanisms could aid the development of novel therapeutic strategies. Therefore, our goal is to encourage scientists to share their studies about the prevention and modulation of inflammatory diseases with biomaterials.
With this research topic, we also aim to gather together frontier research on biomaterials to get a better understanding of the application of anti-inflammatory biomaterials. Therefore, this topic hopes to include preparing novel biomaterials, constructing new drug carrier systems, and investigating underlying anti-inflammatory mechanisms of biomaterials. We welcome submissions in the form of original research, reviews, and comments, including but not limited to the following subtopics:
• The novel preparation method of biomaterial composed of natural bioactive compounds
• The discovery and development of biomaterials-assisted drug delivery strategies
• Investigation of anti-inflammatory mechanisms of biomaterials
• Novel application of biomaterials to inflammation diseases
• In-vitro/ in-vivo evaluation of antioxidant and anti-inflammatory activities of biomaterials
