Ocular Neurodegenerative Diseases: Novel Mechanisms, Diagnosis, and Therapeutic Strategies

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Editorial

01 September 2023

Editorial: Ocular neurodegenerative diseases: novel mechanisms, diagnosis, and therapeutic strategies

Wenyi Wu

,

Yuanjun Li

,

Tu Hu

,

Wensi Tao

, 1 more and

Hetian Lei

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3

Dan Wen

Xiangya Hospital, Central South University

Hetian Lei

Shenzhen Eye Hospital

Wensi Tao

Sylvester Comprehensive Cancer Center, University of Miami Health System

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Ocular neurodegeneration can lead to blindness without timely and appropriate treatment, which includes high myopia, glaucoma, macular degeneration, optic nerve atrophy, retinopathy and so on. In addition, a strong connection between retina and the brain has been shown. Thus, conducting a deeper exploration of retinal disease and visual dysfunction related to brain plasticity is currently one of the hottest areas in neuroscience.
We also have a strong interest in neuronal correction which directly targets the visual deficits in different visual tasks. Studies on visual deficits and rehabilitation have enriched our knowledge of functional eye diseases that participates in ocular neurodegeneration. But a further understanding of different functional eye diseases is needed, such as the clinical relevance of different vision deficits, the underlying neural mechanisms of vision loss, and the plasticity of adult vision. Besides, novel therapy with super-star pharmacological intervention and other creative methods including gene therapy and stem cell therapy also appeal to our audience. The aim of this research is to extend our knowledge related to retinal and visual impairments by combining work of ophthalmology, optometry, psychology, neuroscience, and vision science.
We welcome original research, reviews, mini-reviews, case reports, and perspective articles related to neurodegeneration studies of any disorders of retinal and visual pathway.
Topics may include, but are not limited to:
• Specific pathway which mediates in apoptosis, pyroptosis and ferroptosis in ocular neurodegeneration.
• Interaction and regulation between retina and brain.
• Affective computing, AI-based disease recognition and analysis of visual dysfunction.
• Advanced material delivery in regeneration medicine.
• Novel methods and tools used to cure decreased vision.

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Editors

Dan Wen

Xiangya Hospital, Central South University

Hetian Lei

Shenzhen Eye Hospital

Wensi Tao

Sylvester Comprehensive Cancer Center, University of Miami Health System

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Frontiers in Neuroscience

Visual Neuroscience

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