A high-altitude environment inevitably causes neurological dysfunction or related diseases mainly due to hypobaric hypoxia. Previous studies primarily focused on high-altitude intracranial hypertension caused by brain edema and acute or chronic neurological dysfunction, such as cognitive function decline, memory deterioration, para-equilibrium, and somnipathy. However, most of the physiological and pathophysiological mechanisms underlying the response of the neural system to the high-altitude environment have not been revealed at the clinical and mechanistic levels.
This Research Topic aims to provide a forum for researchers to discover the specific manifestations and related mechanisms of high altitude’s short -, medium - and long-term effects of high altitude on neurological function and to explore the effective drugs, oxygen therapy, and exercise methods to improve neurological dysfunction at high altitude. In addition, we would like to present plateau’s research on cognitive function in neurodegenerative diseases, cerebrovascular diseases, and aging-related neurological diseases.
The topic of this study is high-altitude neurological dysfunctions and diseases. Review, Mini-review, Hypothesis, and Original Research articles are welcome, including but not limited to:
- Cohort studies or cross-sectional studies of high-altitude neurological dysfunctions and diseases
- Studies on cognition, sleep, and balance related to high altitude
- Application of new technologies and methods in the study of high-altitude neurological dysfunctions and diseases
- Intervention study on the high-altitude neurological dysfunctions and diseases
- Simulated or real animal experimental studies of high-altitude nervous system dysfunction or disease, including pathophysiological changes of brain regions, proteomic and post-translational modification studies
- Research on early diagnosis and early warning of high-altitude neurological dysfunctions and diseases
- A follow-up study of brain function changes in altitude and off-altitude adaptation
A high-altitude environment inevitably causes neurological dysfunction or related diseases mainly due to hypobaric hypoxia. Previous studies primarily focused on high-altitude intracranial hypertension caused by brain edema and acute or chronic neurological dysfunction, such as cognitive function decline, memory deterioration, para-equilibrium, and somnipathy. However, most of the physiological and pathophysiological mechanisms underlying the response of the neural system to the high-altitude environment have not been revealed at the clinical and mechanistic levels.
This Research Topic aims to provide a forum for researchers to discover the specific manifestations and related mechanisms of high altitude’s short -, medium - and long-term effects of high altitude on neurological function and to explore the effective drugs, oxygen therapy, and exercise methods to improve neurological dysfunction at high altitude. In addition, we would like to present plateau’s research on cognitive function in neurodegenerative diseases, cerebrovascular diseases, and aging-related neurological diseases.
The topic of this study is high-altitude neurological dysfunctions and diseases. Review, Mini-review, Hypothesis, and Original Research articles are welcome, including but not limited to:
- Cohort studies or cross-sectional studies of high-altitude neurological dysfunctions and diseases
- Studies on cognition, sleep, and balance related to high altitude
- Application of new technologies and methods in the study of high-altitude neurological dysfunctions and diseases
- Intervention study on the high-altitude neurological dysfunctions and diseases
- Simulated or real animal experimental studies of high-altitude nervous system dysfunction or disease, including pathophysiological changes of brain regions, proteomic and post-translational modification studies
- Research on early diagnosis and early warning of high-altitude neurological dysfunctions and diseases
- A follow-up study of brain function changes in altitude and off-altitude adaptation